SCOPe 2.08: Protein: Thymidine kinase, TK1, N-terminal domain

Lineage for Protein: Thymidine kinase, TK1, N-terminal domain

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
division into families based on beta-sheet topologies

Family c.37.1.24: Type II thymidine kinase [117558] (2 proteins)
N-terminal part of Pfam PF00265; parallel beta-sheet of 6 strands, order 324516; topological similarity to the RecA-like proteins, especially CobA (52684)

Protein Thymidine kinase, TK1, N-terminal domain [117559] (4 species)

Species:

Clostridium acetobutylicum [TaxId:1488] [117562] (1 PDB entry)
Uniprot Q97F65
- Domains for 1xx6:
  1. Domain d1xx6a1: 1xx6 A:2-142 [116139]
    Other proteins in same PDB: d1xx6a2, d1xx6b2
    Structural genomics target
    complexed with adp, zn
  2. Domain d1xx6b1: 1xx6 B:2-142 [116141]
    Other proteins in same PDB: d1xx6a2, d1xx6b2
    Structural genomics target
    complexed with adp, zn
Human (Homo sapiens) [TaxId:9606] [117560] (2 PDB entries)
Uniprot P04183 18-191
1. Domains for 1xbt:
  1. Domain d1xbta1: 1xbt A:18-150 [115080]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  2. Domain d1xbtb1: 1xbt B:18-150 [115082]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  3. Domain d1xbtc1: 1xbt C:18-150 [115084]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  4. Domain d1xbtd1: 1xbt D:18-150 [115086]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  5. Domain d1xbte1: 1xbt E:18-150 [115088]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  6. Domain d1xbtf1: 1xbt F:18-150 [115090]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  7. Domain d1xbtg1: 1xbt G:18-150 [115092]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
  8. Domain d1xbth1: 1xbt H:18-150 [115094]
    Other proteins in same PDB: d1xbta2, d1xbtb2, d1xbtc2, d1xbtd2, d1xbte2, d1xbtf2, d1xbtg2, d1xbth2
    complexed with mg, ttp, zn
2. Domains for 2orv:
  1. Domain d2orva1: 2orv A:18-150 [139274]
    Other proteins in same PDB: d2orva2, d2orvb2
    automated match to d1xbta1
    complexed with 4ta, zn
  2. Domain d2orvb1: 2orv B:18-150 [139276]
    Other proteins in same PDB: d2orva2, d2orvb2
    automated match to d1xbta1
    complexed with 4ta, zn
Staphylococcus aureus [TaxId:1280] [225702] (1 PDB entry)
- Domain for 3e2i:
  - Domain d3e2ia1: 3e2i A:7-142 [209362]
    Other proteins in same PDB: d3e2ia2
    automated match to d1xx6a1
    complexed with gol, zn
Ureaplasma urealyticum [TaxId:2130] [117561] (3 PDB entries)
Uniprot Q9PPP5 11-211
1. Domains for 1xmr:
  1. Domain d1xmra3: 1xmr A:11-149 [303356]
    Other proteins in same PDB: d1xmra4, d1xmrb4, d1xmrc4, d1xmrd4
    automated match to d2uz3a1
    complexed with mg, ttp, zn
  2. Domain d1xmrb3: 1xmr B:11-149 [303358]
    Other proteins in same PDB: d1xmra4, d1xmrb4, d1xmrc4, d1xmrd4
    automated match to d2uz3a1
    complexed with mg, ttp, zn
  3. Domain d1xmrc3: 1xmr C:11-149 [303360]
    Other proteins in same PDB: d1xmra4, d1xmrb4, d1xmrc4, d1xmrd4
    automated match to d2uz3a1
    complexed with mg, ttp, zn
  4. Domain d1xmrd3: 1xmr D:11-149 [303362]
    Other proteins in same PDB: d1xmra4, d1xmrb4, d1xmrc4, d1xmrd4
    automated match to d2uz3a1
    complexed with mg, ttp, zn
2. Domains for 2b8t:
  1. Domain d2b8ta1: 2b8t A:11-149 [128109]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    complexed with thm, trs, zn
  2. Domain d2b8tb1: 2b8t B:11-149 [128111]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    automated match to d2b8ta1
    complexed with thm, trs, zn
  3. Domain d2b8tc1: 2b8t C:11-149 [128113]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    automated match to d2b8ta1
    complexed with thm, trs, zn
  4. Domain d2b8td1: 2b8t D:12-149 [128115]
    Other proteins in same PDB: d2b8ta2, d2b8tb2, d2b8tc2, d2b8td2
    automated match to d2b8ta1
    complexed with thm, trs, zn
3. Domains for 2uz3:
  1. Domain d2uz3a1: 2uz3 A:11-149 [140040]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    complexed with mg, ttp, zn
  2. Domain d2uz3b1: 2uz3 B:11-149 [140042]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    complexed with mg, ttp, zn
  3. Domain d2uz3c1: 2uz3 C:11-149 [140044]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    complexed with mg, ttp, zn
  4. Domain d2uz3d1: 2uz3 D:11-149 [140046]
    Other proteins in same PDB: d2uz3a2, d2uz3b2, d2uz3c2, d2uz3d2
    complexed with mg, ttp, zn

More info for Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase

Timeline for Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase:

Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase first appeared in SCOP 1.71
Protein Thymidine kinase, TK1, N-terminal domain from c.37.1.24: Type II thymidine kinase appears in SCOPe 2.07