SCOPe 2.08: Domain d1tlza1: 1tlz A:9-272

Lineage for d1tlza1 (1tlz A:9-272)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.4: Transmembrane beta-barrels [56924] (7 superfamilies)
   not a true fold, gathers together transmembrane barrels of different (n,S)
   annotated by the SCOP(e) curators as 'not a true fold'

4. Superfamily f.4.6: Tsx-like channel [111364] (1 family)
   forms (12,16) barrel
   automatically mapped to Pfam PF03502

5. Family f.4.6.1: Tsx-like channel [111365] (1 protein)
   Pfam PF03502

6. Protein Nucleoside-specific channel-forming protein tsx (NupA) [111366] (1 species)

7. Species Escherichia coli [TaxId:562] [111367] (3 PDB entries)
   Uniprot P22786

8. Domain d1tlza1: 1tlz A:9-272 [107145]
   Other proteins in same PDB: d1tlza2
   complexed with uri

Details for d1tlza1

PDB Entry: 1tlz, 3.1 Å

PDB Description: Tsx structure complexed with uridine

PDB Compounds: (A:) Nucleoside-specific channel-forming protein tsx

SCOPe Domain Sequences for d1tlza1:

Sequence, based on SEQRES records:

>d1tlza1 f.4.6.1 (A:9-272) Nucleoside-specific channel-forming protein tsx (NupA) {Escherichia coli [TaxId: 562]}
lsdwwhqsvnvvgsyhtrfgpqirndtyleyeafakkdwfdfygyadapvffggnsdakg
iwnhgsplfmeieprfsidkltntdlsfgpfkewyfannyiydmgrnkdgrqstwymglg
tdidtglpmslsmnvyakyqwqnygaanenewdgyrfkikyfvpitdlwggqlsyigftn
fdwgsdlgddsgnaingiktrtnnsiasshilalnydhwhysvvarywhdggqwnddael
nfgngnfnvrstgwggylvvgynf

Sequence, based on observed residues (ATOM records):

>d1tlza1 f.4.6.1 (A:9-272) Nucleoside-specific channel-forming protein tsx (NupA) {Escherichia coli [TaxId: 562]}
lsdwwhqsvnvvgsyhtrfgpqirndtyleyeafakkdwfdfygyadapvplfmeieprf
sidkltntdlsfgpfkewyfannyiydmgrnkdgrqstwymglgtdidtglpmslsmnvy
akyqwqnygaanenewdgyrfkikyfvpitdlwggqlsyigftnfdwgsdlgddsgnain
giktrtnnsiasshilalnydhwhysvvarywhdggqwnddaelnfgngnfnvrstgwgg
ylvvgynf

Timeline for d1tlza1:

• d1tlza1 first appeared in SCOP 1.69, called d1tlza_
  
• d1tlza1 appears in SCOPe 2.07