Class a: All alpha proteins [46456] (289 folds) |
Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily) multihelical; consists of two different alpha-helical bundles |
Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) |
Family a.211.1.2: PDEase [48548] (7 proteins) Pfam PF00233; multihelical; can be divided into three subdomains |
Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species) |
Human (Homo sapiens) [TaxId:9606] [101440] (26 PDB entries) Uniprot O76074 534-860 |
Domain d1rkpa_: 1rkp A: [97620] complexed with ibm, mg, zn |
Domain d1t9ra_: 1t9r A: [106725] complexed with cit, po4, zn |
Domain d1t9sa_: 1t9s A: [106726] complexed with 5gp, mg, zn |
Domain d1t9sb_: 1t9s B: [106727] complexed with 5gp, mg, zn |
Domain d1tbfa_: 1tbf A: [106743] complexed with gol, mg, via, zn |
Domain d1udta_: 1udt A: [99221] complexed with mg, via, zn |
Domain d1udua_: 1udu A: [99222] complexed with cia, mg, zn |
Domain d1udub_: 1udu B: [99223] complexed with cia, mg, zn |
Domain d1uhoa_: 1uho A: [107851] complexed with mg, vdn, zn |
Domain d1xoza_: 1xoz A: [115719] complexed with cia, mg, zn |
Domain d1xp0a_: 1xp0 A: [115720] complexed with mg, vdn, zn |
Domain d2chma1: 2chm A:537-858 [130472] complexed with 3p4, mes, mg, zn |
Domain d2h40a_: 2h40 A: [136063] automated match to d1rkpa_ complexed with mg, zn |
Domain d2h42a_: 2h42 A: [136064] automated match to d1rkpa_ complexed with mg, via, zn |
Domain d2h42b_: 2h42 B: [136065] automated match to d1rkpa_ complexed with mg, via, zn |
Domain d2h42c_: 2h42 C: [136066] automated match to d1rkpa_ complexed with mg, via, zn |
Domain d2h44a_: 2h44 A: [136069] automated match to d1rkpa_ complexed with 7ca, mg, zn |
Domain d3b2ra2: 3b2r A:535-860 [154768] Other proteins in same PDB: d3b2ra3 automated match to d1rkpa_ complexed with vdn |
Domain d3b2rb_: 3b2r B: [154769] Other proteins in same PDB: d3b2ra3 automated match to d1rkpa_ complexed with vdn |
Domain d3bjca_: 3bjc A: [155329] automated match to d1t9ra_ complexed with mg, wan, zn |
Domain d3hc8a_: 3hc8 A: [177364] automated match to d1t9sa_ complexed with mg, pd4, zn |
Domain d3hdza_: 3hdz A: [177417] automated match to d1t9sa_ complexed with mg, pd6, zn |
Domain d3tgea_: 3tge A: [185822] automated match to d1t9sa_ complexed with mg, tge, zn |
Domain d3tgga_: 3tgg A: [185823] automated match to d1t9sa_ complexed with 0h3, mg, zn |
Domain d4md6a_: 4md6 A: [257934] automated match to d3b2ra_ complexed with 24e, mg, so4, zn |
Domain d5jo3b_: 5jo3 B: [333772] automated match to d2chma1 complexed with 6lk, zn |
Domain d5zz2a_: 5zz2 A: [357887] automated match to d1rkpa_ complexed with 9m0, mg, so4, zn |
Domain d6acba_: 6acb A: [357705] automated match to d1rkpa_ complexed with 9t9, mg, so4, zn |
Domain d6iwia_: 6iwi A: [377969] automated match to d1rkpa_ complexed with b0c, mg, zn |
Domain d6l6ea_: 6l6e A: [390795] automated match to d1t9ra_ complexed with e6l, mg, so4, zn |
Domain d6vbia_: 6vbi A: [400733] automated match to d1rkpa_ complexed with fza |
Domain d6vbib_: 6vbi B: [400686] automated match to d1rkpa_ complexed with fza |
Timeline for Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx from a.211.1.2: PDEase: