Lineage for d1n4ma2 (1n4m A:643-785)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2718075Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2718076Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2718685Family a.74.1.3: Retinoblastoma tumor suppressor domains [47969] (1 protein)
  6. 2718686Protein Retinoblastoma tumor suppressor domains [47970] (1 species)
    contains an additional C-terminal helix
  7. 2718687Species Human (Homo sapiens) [TaxId:9606] [47971] (7 PDB entries)
  8. 2718695Domain d1n4ma2: 1n4m A:643-785 [79995]
    bound to the transactivation domain (peptide) of E2F-2
    has additional insertions and/or extensions that are not grouped together

Details for d1n4ma2

PDB Entry: 1n4m (more details), 2.2 Å

PDB Description: Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2
PDB Compounds: (A:) Retinoblastoma Pocket

SCOPe Domain Sequences for d1n4ma2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1n4ma2 a.74.1.3 (A:643-785) Retinoblastoma tumor suppressor domains {Human (Homo sapiens) [TaxId: 9606]}
kstslslfykkvyrlaylrlntlcerllsehpelehiiwtlfqhtlqneyelmrdrhldq
immcsmygickvknidlkfkiivtaykdlphavqetfkrvlikeeeydsiivfynsvfmq
rlktnilqyastrpptlspiphi

SCOPe Domain Coordinates for d1n4ma2:

Click to download the PDB-style file with coordinates for d1n4ma2.
(The format of our PDB-style files is described here.)

Timeline for d1n4ma2:

2718695
d1n4ma2 in context of chain
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Domains from same chain:
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d1n4ma1