Lineage for Protein: Retinoblastoma tumor suppressor domains

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2718075Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2718076Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2718685Family a.74.1.3: Retinoblastoma tumor suppressor domains [47969] (1 protein)
  6. 2718686Protein Retinoblastoma tumor suppressor domains [47970] (1 species)
    contains an additional C-terminal helix

Species:

  • 2718687Human (Homo sapiens) [TaxId:9606] [47971] (7 PDB entries)
    1. Domain for 1ad6:
      • 2718698Domain d1ad6a_: 1ad6 A: [18390]
        domain A
        has additional insertions and/or extensions that are not grouped together
    2. Domains for 1gh6:
      1. 2718711Domain d1gh6b1: 1gh6 B:379-583 [65192]
        Other proteins in same PDB: d1gh6a1, d1gh6a2
        has additional insertions and/or extensions that are not grouped together
      2. 2718712Domain d1gh6b2: 1gh6 B:645-772 [65193]
        Other proteins in same PDB: d1gh6a1, d1gh6a2
        has additional insertions and/or extensions that are not grouped together
    3. Domains for 1gux:
      1. 2718688Domain d1guxa_: 1gux A: [18388]
        domains A and B
        has additional insertions and/or extensions that are not grouped together
      2. 2718689Domain d1guxb_: 1gux B: [18389]
        domains A and B
        has additional insertions and/or extensions that are not grouped together
    4. Domains for 1n4m:
      1. 2718694Domain d1n4ma1: 1n4m A:380-581 [79994]
        bound to the transactivation domain (peptide) of E2F-2
        has additional insertions and/or extensions that are not grouped together
      2. 2718695Domain d1n4ma2: 1n4m A:643-785 [79995]
        bound to the transactivation domain (peptide) of E2F-2
        has additional insertions and/or extensions that are not grouped together
      3. 2718696Domain d1n4mb1: 1n4m B:380-581 [79996]
        bound to the transactivation domain (peptide) of E2F-2
        has additional insertions and/or extensions that are not grouped together
      4. 2718697Domain d1n4mb2: 1n4m B:643-785 [79997]
        bound to the transactivation domain (peptide) of E2F-2
        has additional insertions and/or extensions that are not grouped together
    5. Domains for 1o9k:
      1. 2718699Domain d1o9ka_: 1o9k A: [86698]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      2. 2718700Domain d1o9kb_: 1o9k B: [86699]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      3. 2718701Domain d1o9kc_: 1o9k C: [86700]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      4. 2718702Domain d1o9kd_: 1o9k D: [86701]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      5. 2718703Domain d1o9ke_: 1o9k E: [86702]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      6. 2718704Domain d1o9kf_: 1o9k F: [86703]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      7. 2718705Domain d1o9kg_: 1o9k G: [86704]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
      8. 2718706Domain d1o9kh_: 1o9k H: [86705]
        domain A - chains A, C, E, G; domain B - chains B, D, F, H; complexed with E2F peptide, chains P, Q, R, S
        has additional insertions and/or extensions that are not grouped together
    6. Domains for 2r7g:
      1. 2718690Domain d2r7ga1: 2r7g A:380-578 [151637]
        automated match to d1n4ma1
        complexed with so4

        has additional insertions and/or extensions that are not grouped together
      2. 2718691Domain d2r7ga2: 2r7g A:643-785 [151638]
        automated match to d1n4ma2
        complexed with so4

        has additional insertions and/or extensions that are not grouped together
      3. 2718692Domain d2r7gc1: 2r7g C:380-579 [151639]
        automated match to d1n4ma1
        complexed with so4

        has additional insertions and/or extensions that are not grouped together
      4. 2718693Domain d2r7gc2: 2r7g C:643-785 [151640]
        automated match to d1n4ma2
        complexed with so4

        has additional insertions and/or extensions that are not grouped together
    7. Domains for 3pom:
      1. 2718707Domain d3poma1: 3pom A:383-580 [214887]
        automated match to d1n4ma1
        has additional insertions and/or extensions that are not grouped together
      2. 2718708Domain d3poma2: 3pom A:643-786 [214888]
        automated match to d1n4ma2
        has additional insertions and/or extensions that are not grouped together
      3. 2718709Domain d3pomb1: 3pom B:382-579 [214889]
        automated match to d1n4ma1
        has additional insertions and/or extensions that are not grouped together
      4. 2718710Domain d3pomb2: 3pom B:644-785 [214890]
        automated match to d1n4ma2
        has additional insertions and/or extensions that are not grouped together

More info for Protein Retinoblastoma tumor suppressor domains from a.74.1.3: Retinoblastoma tumor suppressor domains

Timeline for Protein Retinoblastoma tumor suppressor domains from a.74.1.3: Retinoblastoma tumor suppressor domains: