Lineage for d1he8a4 (1he8 A:726-1084)
- Root: SCOPe 2.06
Class d: Alpha and beta proteins (a+b) [53931] (385 folds) 
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helicalSuperfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) 
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain [56171] (1 protein) Protein Phoshoinositide 3-kinase (PI3K), catalytic domain [56172] (2 species) 
Species Human (Homo sapiens) [TaxId:9606] [56174] (65 PDB entries) 
Domain d1he8a4: 1he8 A:726-1084 [41717]
Other proteins in same PDB: d1he8a1, d1he8a2, d1he8a3, d1he8b_
complexed with gnp, mg
Details for d1he8a4
PDB Entry: 1he8 (more details), 3 Å
PDB Description: ras g12v - pi 3-kinase gamma complex
PDB Compounds: (A:) phosphatidylinositol 3-kinase catalytic subunit, gamma isoformSCOPe Domain Sequences for d1he8a4:
Sequence, based on SEQRES records: (download)
>d1he8a4 d.144.1.4 (A:726-1084) Phoshoinositide 3-kinase (PI3K), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
tamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrv
pydpglkagalaiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvgntgafkde
vlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhidf
ghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtn
lliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqf
Sequence, based on observed residues (ATOM records): (download)
>d1he8a4 d.144.1.4 (A:726-1084) Phoshoinositide 3-kinase (PI3K), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
tamlhdftqqvqviemlqkvtldikslssqvisqlkqklenlqnsqlpesfrvpydpglk
agalaiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrime
siwetesldlcllpygcistgdkigmieivkdattiakiqqstfkdevlnhwlkekspte
ekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhidfghervpfvltpdf
lfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtdieyirdaltvgkn
eedakkyfldqievcrdkgwtvqf
SCOPe Domain Coordinates for d1he8a4:
Click to download the PDB-style file with coordinates for d1he8a4.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d1he8a4:
- d1he8a4 first appeared (with stable ids) in SCOP 1.55
- d1he8a4 appears in SCOPe 2.05
- d1he8a4 appears in SCOPe 2.07
- d1he8a4 appears in the current release, SCOPe 2.08
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