SCOPe 2.08: Structural Classification of Proteins

PDB entry 4g7h

View 4g7h on RCSB PDB site
Description: Crystal structure of Thermus thermophilus transcription initiation complex
Class: transcription, transferase/DNA
Keywords: protein-DNA complex, transcription initiation complex, RNAP-promoter complex, RNAP-promoter open complex, open complex, RPo, RNA polymerase, transcription initiation, transcription Initiation factor sigma A, promoter DNA, nucleoid, TRANSCRIPTION, TRANSFERASE-DNA complex
Deposited on 2012-07-20, released 2012-10-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-12-12, with a file datestamp of 2012-12-07.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.188
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: DNA-directed RNA polymerase subunit alpha
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6
Domains in SCOPe 2.08: d4g7ha1, d4g7ha2
Chain 'B':
Compound: DNA-directed RNA polymerase subunit alpha
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6
Domains in SCOPe 2.08: d4g7hb1, d4g7hb2
Chain 'C':
Compound: DNA-directed RNA polymerase subunit beta
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE9 (0-End)
Domains in SCOPe 2.08: d4g7hc_
Chain 'D':
Compound: DNA-directed RNA polymerase subunit beta'
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE8
Domains in SCOPe 2.08: d4g7hd_
Chain 'E':
Compound: DNA-directed RNA polymerase subunit omega
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE7
Domains in SCOPe 2.08: d4g7he_
Chain 'F':
Compound: RNA polymerase sigma factor
Species: Thermus thermophilus [TaxId:300852]
Gene: rpoD, TTHA0532
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SKW1 (Start-442)
Domains in SCOPe 2.08: d4g7hf1, d4g7hf2, d4g7hf3
Chain 'G':
Compound: 5'-d(*cp*cp*t*gp*cp*ap*tp*cp*cp*gp*tp*gp*ap*gp*tp*cp*gp*ap*g)-3'
Chain 'H':
Compound: 5'-d(*tp*ap*tp*ap*ap*tp*gp*gp*gp*ap*gp*cp*tp*gp*tp*cp*ap*cp*gp*gp*ap*tp*gp*cp*ap*gp*g)-3'
Chain 'K':
Compound: DNA-directed RNA polymerase subunit alpha
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6
Domains in SCOPe 2.08: d4g7hk1, d4g7hk2
Chain 'L':
Compound: DNA-directed RNA polymerase subunit alpha
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SHR6
Domains in SCOPe 2.08: d4g7hl1, d4g7hl2
Chain 'M':
Compound: DNA-directed RNA polymerase subunit beta
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE9 (0-End)
Domains in SCOPe 2.08: d4g7hm_
Chain 'N':
Compound: DNA-directed RNA polymerase subunit beta'
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE8
Domains in SCOPe 2.08: d4g7hn_
Chain 'O':
Compound: DNA-directed RNA polymerase subunit omega
Species: Thermus thermophilus [TaxId:300852]
Database cross-references and differences (RAF-indexed):
- Uniprot Q8RQE7
Domains in SCOPe 2.08: d4g7ho_
Chain 'P':
Compound: RNA polymerase sigma factor
Species: Thermus thermophilus [TaxId:300852]
Gene: rpoD, TTHA0532
Database cross-references and differences (RAF-indexed):
- Uniprot Q5SKW1 (Start-442)
Domains in SCOPe 2.08: d4g7hp1, d4g7hp2, d4g7hp3
Chain 'Q':
Compound: 5'-d(*cp*cp*t*gp*cp*ap*tp*cp*cp*gp*tp*gp*ap*gp*tp*cp*gp*ap*g)-3'
Chain 'R':
Compound: 5'-d(*tp*ap*tp*ap*ap*tp*gp*gp*gp*ap*gp*cp*tp*gp*tp*cp*ap*cp*gp*gp*ap*tp*gp*cp*ap*gp*g)-3'
Heterogens: MG, ZN, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4g7hA (A:)
mldsklkapvftvrtqgreygefvleplergfgvtlgnplrrillssipgtavtsvyied
vlhefstipgvkedvveiilnlkelvvrflnpslqtvtlllkaegpkevkardflpvadv
eimnpdlhiatleeggrlnmevrvdrgvgyvpaekhgikdrinaipvdavfspvrrvafq
vedtrlgqrtdldkltlriwtdgsvtplealnqaveilrehltyfsnpqaaavaapeeak
epeappeqeeeldlpleelglstrvlhslkeegiesvrallalnlkdlknipgigersle
eikealekkgftlke