SCOPe 2.08: Structural Classification of Proteins

PDB entry 3ly6

View 3ly6 on RCSB PDB site
Description: Crystal structure of human transglutaminase 2 complex with adenosine 5' Triphosphate
Class: Transferase
Keywords: transglutaminase, Acyltransferase, Diabetes mellitus, Disease mutation, Metal-binding, Phosphoprotein, Transferase
Deposited on 2010-02-26, released 2010-08-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-08-18, with a file datestamp of 2010-08-13.
Experiment type: XRAY
Resolution: 3.14 Å
R-factor: 0.233
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Protein-glutamine gamma-glutamyltransferase 2
Species: Homo sapiens [TaxId:9606]
Gene: TGM2
Database cross-references and differences (RAF-indexed):
- Uniprot P21980 (Start-686)
  - see remark 999 (223)
  - expression tag (687)
Domains in SCOPe 2.08: d3ly6a1, d3ly6a2, d3ly6a3, d3ly6a4, d3ly6a5
Chain 'B':
Compound: Protein-glutamine gamma-glutamyltransferase 2
Species: Homo sapiens [TaxId:9606]
Gene: TGM2
Database cross-references and differences (RAF-indexed):
- Uniprot P21980 (Start-686)
  - see remark 999 (223)
  - expression tag (687)
Domains in SCOPe 2.08: d3ly6b1, d3ly6b2, d3ly6b3, d3ly6b4, d3ly6b5
Chain 'C':
Compound: Protein-glutamine gamma-glutamyltransferase 2
Species: Homo sapiens [TaxId:9606]
Gene: TGM2
Database cross-references and differences (RAF-indexed):
- Uniprot P21980 (Start-686)
  - see remark 999 (223)
  - expression tag (687)
Domains in SCOPe 2.08: d3ly6c1, d3ly6c2, d3ly6c3, d3ly6c4, d3ly6c5
Heterogens: ATP

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3ly6A (A:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyeasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfedgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnlnlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdllplhmg
lhklvvnfesdklkavkgfrnviigpalehhhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3ly6A (A:)
elvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyeasvdsltfsvvt
gpapsqeagtkarfplrdavgdwtatvvdqqdctlslqlttpanapiglyrlsleastgy
qgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipwnfgqf
edgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgrwdnny
gdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtnynsah
dqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldptpqeks
egtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrslivglk
istksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvgqsmnm
gsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnlnlepfseksvplc
ilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqkrklva
evslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdllplhmglhklv
vnfesdklkavkgfrnviigpal

Chain 'B':
Sequence, based on SEQRES records: (download)

>3ly6B (B:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyeasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfedgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnlnlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdllplhmg
lhklvvnfesdklkavkgfrnviigpalehhhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3ly6B (B:)
elvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyeasvdsltfsvvt
gpapsqeagtkarfplrdavgdwtatvvdqqdctlslqlttpanapiglyrlsleastgy
qgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipwnfgqf
edgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgrwdnny
gdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtnynsah
dqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldptpqeks
egtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrslivglk
istksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvgqsmnm
gsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnlnlepfseksvplc
ilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqkrklva
evslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdllplhmglhklv
vnfesdklkavkgfrnviigpal

Chain 'C':
Sequence, based on SEQRES records: (download)

>3ly6C (C:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyeasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfedgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnlnlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdllplhmg
lhklvvnfesdklkavkgfrnviigpalehhhhhhhh

Sequence, based on observed residues (ATOM records): (download)

>3ly6C (C:)
elvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyeasvdsltfsvvt
gpapsqeagtkarfplrdavgdwtatvvdqqdctlslqlttpanapiglyrlsleastgy
qgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipwnfgqf
edgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgrwdnny
gdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtnynsah
dqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldptpqeks
egtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrslivglk
istksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvgqsmnm
gsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnlnlepfseksvplc
ilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqkrklva
evslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdllplhmglhklv
vnfesdklkavkgfrnviigpal