Lineage for Protein: Flap endonuclease-1 (Fen-1 nuclease)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2921858Fold c.120: PIN domain-like [88722] (1 superfamily)
    3 layers, a/b/a; core: parallel beta-sheet of 5 strands, order 32145
  4. 2921859Superfamily c.120.1: PIN domain-like [88723] (4 families) (S)
  5. 2921920Family c.120.1.2: 5' to 3' exonuclease catalytic domain [53045] (4 proteins)
    contains an alpha-helical arch and additional strand 6 antiparallel to the rest; strand order 321456; similarity to the resolvase-like fold
  6. 2921927Protein Flap endonuclease-1 (Fen-1 nuclease) [53052] (5 species)

Species:

  1. 2921928Archaeoglobus fulgidus [TaxId:2234] [102272] (2 PDB entries)
    1. Domains for 1rxv:
      1. 2921930Domain d1rxva2: 1rxv A:4-219 [98056]
        Other proteins in same PDB: d1rxva1, d1rxvb1
        protein/DNA complex
        missing some secondary structures that made up less than one-third of the common domain
      2. 2921931Domain d1rxvb2: 1rxv B:4-219 [98058]
        Other proteins in same PDB: d1rxva1, d1rxvb1
        protein/DNA complex
        missing some secondary structures that made up less than one-third of the common domain
    2. Domain for 1rxw:
      • 2921929Domain d1rxwa2: 1rxw A:3-219 [98060]
        Other proteins in same PDB: d1rxwa1
        protein/DNA complex
        missing some secondary structures that made up less than one-third of the common domain
  2. 2921932Human (Homo sapiens) [TaxId:9606] [142118] (1 PDB entry)
    Uniprot P39748 2-217
  3. 2921936Methanococcus jannaschii [TaxId:2190] [53053] (2 PDB entries)
    1. Domain for 1a76:
      • 2921938Domain d1a76a2: 1a76 A:2-208 [33361]
        Other proteins in same PDB: d1a76a1
        complexed with mn
        missing some secondary structures that made up less than one-third of the common domain
    2. Domain for 1a77:
      • 2921937Domain d1a77a2: 1a77 A:2-208 [33360]
        Other proteins in same PDB: d1a77a1
        complexed with mg
        missing some secondary structures that made up less than one-third of the common domain
  4. 2921939Pyrococcus furiosus [TaxId:2261] [53055] (1 PDB entry)
  5. 2921942Pyrococcus horikoshii [TaxId:53953] [82436] (1 PDB entry)
    • Domains for 1mc8:
      1. 2921943Domain d1mc8a2: 1mc8 A:2-220 [78946]
        Other proteins in same PDB: d1mc8a1, d1mc8b1
        mutant
        missing some secondary structures that made up less than one-third of the common domain
      2. 2921944Domain d1mc8b2: 1mc8 B:2-220 [78948]
        Other proteins in same PDB: d1mc8a1, d1mc8b1
        mutant
        missing some secondary structures that made up less than one-third of the common domain

More info for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain

Timeline for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain: