SCOPe 2.01: Family c.1.8.3: beta-glycanases

Lineage for Family c.1.8.3: beta-glycanases

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

5. Family c.1.8.3: beta-glycanases [51487] (27 proteins)
   consist of a number of sequence families

Proteins:

1. Alkaline cellulase K catalytic domain [63906] (1 species)

   • Species Bacillus sp. [TaxId:1409] [63907] (2 PDB entries)

2. Alpha-L-arabinofuranosidase, catalytic domain [102075] (2 species)
   glycosyl hydrolase family 51

   1. Species Bacillus stearothermophilus [TaxId:1422] [102076] (4 PDB entries)

   2. Species Clostridium thermocellum [TaxId:1515] [141779] (2 PDB entries)
      Uniprot Q4CJG5 17-386

3. Beta-1,4-galactanase [89469] (4 species)

   1. Species Bacillus licheniformis [TaxId:1402] [117367] (4 PDB entries)
      Uniprot Q65CX5 36-422 ! Uniprot Q65CX5 28-424

   2. Species Fungus (Aspergillus aculeatus) [TaxId:5053] [89470] (2 PDB entries)

   3. Species Fungus (Humicola insolens) [TaxId:34413] [89472] (1 PDB entry)

   4. Species Thielavia heterothallica, aka Myceliophthora thermophila [TaxId:78579] [89471] (2 PDB entries)
      Myceliophthora thermophila is the anamorph name whilst Thielavia heterothallica is the teleomorph name

4. Beta-D-xylosidase, catalytic domain [102077] (2 species)
   glycosyl hydrolase family 39

   1. Species Bacillus stearothermophilus [TaxId:1422] [141780] (3 PDB entries)
      Uniprot Q9ZFM2 15-361

   2. Species Thermoanaerobacterium saccharolyticum [TaxId:28896] [102078] (2 PDB entries)

5. beta-Galactosidase, domain 3 [51510] (2 species)

   1. Species Arthrobacter sp. c2-2 [TaxId:192168] [141778] (1 PDB entry)
      Uniprot Q8KRF6 313-609

   2. Species Escherichia coli [TaxId:562] [51511] (25 PDB entries)
      Uniprot P00722

6. beta-Glucuronidase, domain 3 [51512] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [51513] (1 PDB entry)

7. Beta-mannanase [51502] (4 species)

   1. Species Bacillus sp. JAMB-602 [TaxId:244966] [141775] (1 PDB entry)
      Uniprot Q4W8M3 34-490
      contains additional C-terminal domain (CBM)

   2. Species Thermobifida fusca [TaxId:2021] [51503] (3 PDB entries)

   3. Species Tomato (Lycopersicon esculentum) [TaxId:4081] [141774] (1 PDB entry)
      Uniprot Q93WT4 30-399

   4. Species Trichoderma reesei [TaxId:51453] [51504] (5 PDB entries)

8. endo-1,4-beta-mannosidase [141781] (1 species)

   • Species Blue mussel (Mytilus edulis) [TaxId:6550] [141782] (1 PDB entry)
     Uniprot Q8WPJ2 18-367

9. Endocellulase E1 [51497] (1 species)

   • Species Acidothermus cellulolyticus [TaxId:28049] [51498] (2 PDB entries)

10. Endocellulase EngI [75066] (1 species)

    • Species Thermoascus aurantiacus [TaxId:5087] [75067] (2 PDB entries)

11. Endoglucanase Cel5a [51499] (4 species)

    1. Species Bacillus agaradhaerens [TaxId:76935] [51500] (19 PDB entries)
       Uniprot O85465 30-329

    2. Species Bacillus subtilis [TaxId:1423] [75068] (1 PDB entry)

    3. Species Erwinia chrysanthemi [TaxId:556] [51501] (1 PDB entry)

    4. Species Pseudoalteromonas haloplanktis [TaxId:228] [141773] (2 PDB entries)
       Uniprot O86099 33-325

12. Endoglucanase CelA [51491] (1 species)

    • Species Clostridium cellulolyticum [TaxId:1521] [51492] (1 PDB entry)

13. Endoglucanase CelC [51493] (1 species)

    • Species Clostridium thermocellum [TaxId:1515] [51494] (3 PDB entries)

14. Endoglucanase H N-terminal domain [141783] (1 species)

    • Species Clostridium thermocellum [TaxId:1515] [141784] (2 PDB entries)
      Uniprot P16218 29-304! Uniprot P16218 31-304

15. Endoglucanase homologue TM1752 [102066] (1 species)

    • Species Thermotoga maritima [TaxId:2336] [102067] (1 PDB entry)

16. Exo-beta-(1,3)-glucanase [51495] (2 species)

    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [102065] (1 PDB entry)

    2. Species Yeast (Candida albicans) [TaxId:5476] [51496] (4 PDB entries)

17. Exochitosanase CsxA [159383] (1 species)

    • Species Amycolatopsis orientalis [TaxId:31958] [159384] (1 PDB entry)
      Uniprot Q56F26 336-674

18. Exomannosidase [102068] (1 species)
    mannosyl-oligosaccharide glucosidase

    • Species Cellvibrio mixtus [TaxId:39650] [102069] (2 PDB entries)
      Uniprot Q6QT42 46-455

19. Five-domain beta-mannosidase, domain 3 [159385] (1 species)

    • Species Bacteroides thetaiotaomicron [TaxId:818] [159386] (9 PDB entries)
      Uniprot Q8AAK6 330-678! Uniprot Q8AAK6 331-678

20. Glucosylceramidase, catalytic domain [89473] (1 species)
    acid-beta-glucosidase; glycosyl hydrolase family 30; contains additional beta-domain similar to one found in alpha amylases

    • Species Human (Homo sapiens) [TaxId:9606] [89474] (11 PDB entries)

21. Glycosyl hydrolase family 5 xylanase, catalytic domain [102073] (1 species)
    overall domain organization is similar to the homologous glucosylceramidase

    • Species Erwinia chrysanthemi [TaxId:556] [102074] (1 PDB entry)

22. Mannanase A, ManA [63908] (2 species)

    1. Species Cellulomonas fimi [TaxId:1708] [141776] (2 PDB entries)
       Uniprot Q9XCV5 55-420

    2. Species Pseudomonas cellulosa (Cellvibrio japonicus) [TaxId:155077] [63909] (5 PDB entries)

23. Plant beta-glucanases [51507] (3 species)

    1. Species Banana (Musa acuminata), 1,3-beta-glucanase [TaxId:4641] [141777] (1 PDB entry)
       Uniprot O22317 29-340

    2. Species Barley (Hordeum vulgare), 1,3-1,4-beta-glucanase [TaxId:4513] [51509] (2 PDB entries)

    3. Species Barley (Hordeum vulgare), 1,3-beta-glucanase [TaxId:4513] [51508] (1 PDB entry)

24. Xylanase [51488] (6 species)

    1. Species Bacillus stearothermophilus, Ixt6 [TaxId:1422] [102063] (7 PDB entries)
       intra-cellular xylanase

    2. Species Bacillus stearothermophilus, Xt6 [TaxId:1422] [69386] (5 PDB entries)
       Uniprot P40943

    3. Species Cellvibrio mixtus [TaxId:39650] [102064] (4 PDB entries)

    4. Species Clostridium thermocellum, XynZ [TaxId:1515] [51489] (1 PDB entry)
       belongs to family F

    5. Species Fungus (Penicillium simplicissimum) [TaxId:69488] [51490] (1 PDB entry)
       belongs to family 10

    6. Species Thermotoga maritima [TaxId:2336] [141772] (1 PDB entry)
       Uniprot Q9WXS5 23-346

25. Xylanase 10c [102071] (1 species)
    Endo-beta-1,4-xylanase

    • Species Pseudomonas cellulosa (Cellvibrio japonicus) [TaxId:155077] [102072] (2 PDB entries)

26. Xylanase A, catalytic core [51514] (8 species)

    1. Species Cellulomonas fimi [TaxId:1708] [51520] (14 PDB entries)
       synonym: beta-1,4-glycanase Cex

    2. Species Emericella nidulans (Aspergillus nidulans) [TaxId:162425] [110350] (1 PDB entry)
       Uniprot Q00177

    3. Species Fungus (Penicillium simplicissimum) [TaxId:69488] [51516] (7 PDB entries)

    4. Species Pseudomonas fluorescens [TaxId:294] [51517] (7 PDB entries)
       Uniprot P14768 265-610

    5. Species Streptomyces halstedii [TaxId:1944] [102070] (1 PDB entry)

    6. Species Streptomyces lividans [TaxId:1916] [51515] (9 PDB entries)
       Uniprot P26514 43-344

    7. Species Streptomyces olivaceoviridis [TaxId:1921] [51519] (12 PDB entries)
       Uniprot Q7SI98
       N-terminal domain; fused with a ricin A-like beta-trefoil domain

    8. Species Thermoascus aurantiacus [TaxId:5087] [51518] (10 PDB entries)

27. automated matches [190057] (11 species)
    not a true protein

    1. Species Bacillus agaradhaerens [TaxId:76935] [187246] (1 PDB entry)

    2. Species Bacillus halodurans [TaxId:86665] [188453] (1 PDB entry)

    3. Species Bacillus licheniformis [TaxId:1402] [187025] (3 PDB entries)

    4. Species Bacillus sp. [TaxId:65673] [187690] (2 PDB entries)

    5. Species Bacillus sp. [TaxId:89769] [189058] (3 PDB entries)

    6. Species Clostridium thermocellum [TaxId:1515] [187247] (4 PDB entries)

    7. Species Pseudomonas cellulosa (Cellvibrio japonicus) [TaxId:155077] [188920] (1 PDB entry)

    8. Species Rubber tree (Hevea brasiliensis) [TaxId:3981] [189057] (2 PDB entries)

    9. Species Thermoascus aurantiacus [TaxId:5087] [190006] (1 PDB entry)

    10. Species Thermotoga petrophila [TaxId:390874] [189941] (2 PDB entries)

    11. Species Yeast (Candida albicans) [TaxId:5476] [188406] (5 PDB entries)

More info for Family c.1.8.3: beta-glycanases

Timeline for Family c.1.8.3: beta-glycanases:

• Family c.1.8.3: beta-glycanases first appeared (with stable ids) in SCOP 1.55
  
• Family c.1.8.3: beta-glycanases appears in SCOP 1.75
  
• Family c.1.8.3: beta-glycanases appears in SCOPe 2.02
  
• Family c.1.8.3: beta-glycanases appears in the current release, SCOPe 2.08