Lineage for Family c.1.2.1: Histidine biosynthesis enzymes

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 968086Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 968402Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families) (S)
  5. 968403Family c.1.2.1: Histidine biosynthesis enzymes [51367] (3 proteins)
    structural evidence for the gene duplication within the barrel fold

Proteins:

  1. 968404Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF [51370] (4 species)
    1. 968405Species Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId:4932] [69379] (4 PDB entries)
    2. 968414Species Pyrobaculum aerophilum [TaxId:13773] [69380] (1 PDB entry)
    3. 968417Species Thermotoga maritima [TaxId:2336] [51371] (3 PDB entries)
    4. 968423Species Thermus thermophilus [TaxId:274] [82237] (1 PDB entry)
  2. 968425Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368] (2 species)
    1. 968426Species Streptomyces coelicolor [TaxId:1902] [141744] (2 PDB entries)
      Uniprot P16250 2-240
    2. 968429Species Thermotoga maritima [TaxId:2336] [51369] (2 PDB entries)
  3. 968434automated matches [190186] (3 species)
    not a true protein
    1. 968435Species Mycobacterium tuberculosis [TaxId:83332] [189657] (3 PDB entries)
    2. 968442Species Streptomyces coelicolor [TaxId:1902] [189237] (1 PDB entry)
    3. 968444Species Thermotoga maritima [TaxId:2336] [186925] (3 PDB entries)

More info for Family c.1.2.1: Histidine biosynthesis enzymes

Timeline for Family c.1.2.1: Histidine biosynthesis enzymes: