Lineage for Family c.1.2.1: Histidine biosynthesis enzymes

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2079053Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families) (S)
  5. 2079054Family c.1.2.1: Histidine biosynthesis enzymes [51367] (3 protein domains)
    structural evidence for the gene duplication within the barrel fold
    automatically mapped to Pfam PF00977

Protein Domains:

  1. 2079055Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF [51370] (4 species)
    1. 2079056Species Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId:4932] [69379] (4 PDB entries)
    2. 2079065Species Pyrobaculum aerophilum [TaxId:13773] [69380] (1 PDB entry)
    3. 2079068Species Thermotoga maritima [TaxId:2336] [51371] (5 PDB entries)
    4. 2079080Species Thermus thermophilus [TaxId:274] [82237] (1 PDB entry)
  2. 2079082Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368] (2 species)
    1. 2079083Species Streptomyces coelicolor [TaxId:1902] [141744] (1 PDB entry)
      Uniprot P16250 2-240
    2. 2079085Species Thermotoga maritima [TaxId:2336] [51369] (2 PDB entries)
  3. 2079090automated matches [190186] (10 species)
    not a true protein
    1. 2079091Species Actinomyces urogenitalis [TaxId:525246] [269148] (1 PDB entry)
    2. 2079093Species Arthrobacter aurescens [TaxId:43663] [260126] (1 PDB entry)
    3. 2079095Species Corynebacterium efficiens [TaxId:152794] [226694] (1 PDB entry)
    4. 2079098Species Mycobacterium tuberculosis [TaxId:83332] [189657] (4 PDB entries)
    5. 2079106Species Streptomyces coelicolor [TaxId:100226] [277529] (1 PDB entry)
    6. 2079108Species Streptomyces coelicolor [TaxId:1902] [189237] (2 PDB entries)
    7. 2079111Species Streptomyces sp. [TaxId:465541] [259607] (2 PDB entries)
    8. 2079114Species Streptomyces sviceus [TaxId:463191] [258540] (2 PDB entries)
    9. 2079117Species Thermotoga maritima [TaxId:2336] [186925] (4 PDB entries)
    10. 2283013Species Thermotoga maritima [TaxId:243274] [326314] (1 PDB entry)

More info for Family c.1.2.1: Histidine biosynthesis enzymes

Timeline for Family c.1.2.1: Histidine biosynthesis enzymes: