SCOPe 2.01: Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.01
Class a: All alpha proteins [46456] (284 folds)
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
Superfamily a.26.1: 4-helical cytokines [47266] (3 families)
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
contains an additional helix in one of the crossover connections
Protein Interferon-alpha 2a [47314] (1 species)
Species Human (Homo sapiens) [TaxId:9606] [47315] (2 PDB entries)

Domain(s) for 1itf:
- Domain d1itfa_: 1itf A: [16899]
Domain(s) for 2hym:
- Domain d2hymb1: 2hym B:1-165 [136900]
  Other proteins in same PDB: d2hyma1, d2hyma2
  automatically matched to d1itf__

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a:

Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a appears in SCOP 1.75
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a appears in SCOPe 2.02
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 Interferon-alpha 2a appears in the current release, SCOPe 2.08