SCOPe 2.01: Domain d2usna_: 2usn A:

Lineage for d2usna_ (2usn A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Stromelysin-1 (MMP-3) [55536] (1 species)

7. Species Human (Homo sapiens), fibroblast [TaxId:9606] [55537] (37 PDB entries)

8. Domain d2usna_: 2usn A: [40376]
   complexed with ca, in8, zn

Details for d2usna_

PDB Entry: 2usn, 2.2 Å

PDB Description: crystal structure of the catalytic domain of human fibroblast stromelysin-1 inhibited with thiadiazole inhibitor pnu-141803

PDB Compounds: (A:) stromelysin-1

SCOPe Domain Sequences for d2usna_:

Sequence; same for both SEQRES and ATOM records:

>d2usna_ d.92.1.11 (A:) Stromelysin-1 (MMP-3) {Human (Homo sapiens), fibroblast [TaxId: 9606]}
frtfpgipkwrkthltyrivnytpdlpkdavdsavekalkvweevtpltfsrlyegeadi
misfavrehgdfypfdgpgnvlahayapgpgingdahfdddeqwtkdttgtnlflvaahe
ighslglfhsantealmyplyhsltdltrfrlsqddingiqslyg

Timeline for d2usna_:

• d2usna_ first appeared (with stable ids) in SCOP 1.55, called d2usn__
  
• d2usna_ appears in SCOP 1.75
  
• d2usna_ appears in SCOPe 2.02
  
• d2usna_ appears in the current release, SCOPe 2.08