SCOPe 2.08: Domain d6x1gb1: 6x1g B:1-177

Lineage for d6x1gb1 (6x1g B:1-177)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rac [52595] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52596] (41 PDB entries)

8. Domain d6x1gb1: 6x1g B:1-177 [396254]
   Other proteins in same PDB: d6x1gb2, d6x1gd2
   automated match to d5o33a_
   complexed with mg

Details for d6x1gb1

PDB Entry: 6x1g, 1.6 Å

PDB Description: crystal structure of a gef domain from the orientia tsutsugamushi protein otdub in complex with rac1

PDB Compounds: (B:) ras-related c3 botulinum toxin substrate 1

SCOPe Domain Sequences for d6x1gb1:

Sequence; same for both SEQRES and ATOM records:

>d6x1gb1 c.37.1.8 (B:1-177) Rac {Human (Homo sapiens) [TaxId: 9606]}
mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl

Timeline for d6x1gb1:

• d6x1gb1 first appeared in SCOPe 2.07