SCOPe 2.08: Domain d6w3za_: 6w3z A:

Lineage for d6w3za_ (6w3z A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.1: Deoxyhypusine synthase, DHS [52468] (2 proteins)
   automatically mapped to Pfam PF01916

6. Protein automated matches [396027] (1 species)
   not a true protein

7. Species Nematode (Brugia malayi) [TaxId:6279] [396028] (1 PDB entry)

8. Domain d6w3za_: 6w3z A: [396029]
   automated match to d1dhsa_
   complexed with cl, gol, nad

Details for d6w3za_

PDB Entry: 6w3z, 2.3 Å

PDB Description: crystal structure of brugia malayi deoxyhypusine synthase (dhps)

PDB Compounds: (A:) BMA-DHPS-1, isoform a

SCOPe Domain Sequences for d6w3za_:

Sequence, based on SEQRES records:

>d6w3za_ c.31.1.1 (A:) automated matches {Nematode (Brugia malayi) [TaxId: 6279]}
nckfdvhiaemsvlkksstmpadstiikgydfneginydalldqymstgfqashfaqavq
qintmltireeqfegdhtlpypegkqkractiflgytsnlvtsgvrenirylvehdlvdc
ivtsaggveedlikclapsylgafdldgktlrhnglnragniiipnnnycqfedwlmpil
dsceleqknndfswtpsklidrlgaeindkrsicywahrnripvfspaltdgsigdmlyf
hsfrnggikldivedlrhintmavrsnrtgvillgggvmkhhinnanlmrngsdyavyvn
tgqefdgsdsgarpdeavswgkvrsdcrpvkiyadatlvfpllvaktfarhvqqk

Sequence, based on observed residues (ATOM records):

>d6w3za_ c.31.1.1 (A:) automated matches {Nematode (Brugia malayi) [TaxId: 6279]}
nckfdvhiaemsvlkksstmpadstiikgydfneginydalldqymstgfqashfaqavq
qintmltireeqfegdhtlpypegkqkractiflgytsnlvtsgvrenirylvehdlvdc
ivtsaggveedlikclapsylgafdldgktlrhnglnragniiipnnnycqfedwlmpil
dsceleqknndfswtpsklidrlgaeindkrsicywahrnripvfspaltdgsigdmlyf
hgikldivedlrhintmavrsnrtgvillgggvmkhhinnanlmrngsdyavyvntgqef
dgsdsgarpdeavswgkvrsdcrpvkiyadatlvfpllvaktfarhvqqk

Timeline for d6w3za_:

• d6w3za_ first appeared in SCOPe 2.07