SCOPe 2.08: Domain d6y80a_: 6y80 A:

Lineage for d6y80a_ (6y80 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase p38 [56129] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56131] (111 PDB entries)

8. Domain d6y80a_: 6y80 A: [382240]
   automated match to d4aaca_
   complexed with ca, cl, ofz, sb4, so4

Details for d6y80a_

PDB Entry: 6y80, 1.24 Å

PDB Description: fragment kcl_916 in complex with map kinase p38-alpha

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d6y80a_:

Sequence, based on SEQRES records:

>d6y80a_ d.144.1.7 (A:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedselkildfglarhtddemtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpga
ellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqala
hayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeeme

Sequence, based on observed residues (ATOM records):

>d6y80a_ d.144.1.7 (A:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedselkildfglaryvatrwyrape
imlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkiss
esarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyh
dpddepvadpydqsfesrdllidewksltydevisfvpppldqeeme

Timeline for d6y80a_:

• d6y80a_ first appeared in SCOPe 2.07