SCOPe 2.08: Domain d6q3ya_: 6q3y A:

Lineage for d6q3ya_ (6q3y A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1052 PDB entries)

8. Domain d6q3ya_: 6q3y A: [365667]
   automated match to d6czua_
   complexed with edo, hg5

Details for d6q3ya_

PDB Entry: 6q3y, 1.2 Å

PDB Description: crystal structure of the first bromodomain of human brd4 in complex with the inhibitor 16i

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d6q3ya_:

Sequence; same for both SEQRES and ATOM records:

>d6q3ya_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
elpt

Timeline for d6q3ya_:

• d6q3ya_ first appeared in SCOPe 2.07