Lineage for Fold a.29: Bromodomain-like

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2316812Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology

Superfamilies:

  1. 2316813a.29.2: Bromodomain [47370] (2 families) (S)
  2. 2317865a.29.3: Acyl-CoA dehydrogenase C-terminal domain-like [47203] (3 families) (S)
    multidomain flavoprotein; N-terminal domain is all-alpha; the middle domain is open (5,8) barrel
  3. 2318222a.29.5: alpha-ketoacid dehydrogenase kinase, N-terminal domain [69012] (2 families) (S)
    automatically mapped to Pfam PF10436
  4. 2318297a.29.6: Plant invertase/pectin methylesterase inhibitor [101148] (2 families) (S)
    contains a short alpha-hairpin at the N-terminal extension
  5. 2318333a.29.7: Mob1/phocein [101152] (2 families) (S)
    common fold is elaborated with additional short helices; contains a zinc-binding site
    automatically mapped to Pfam PF03637
  6. 2318353a.29.8: Bacteriocin immunity protein-like [109797] (2 families) (S)
  7. 2318367a.29.9: LemA-like [140478] (1 family) (S)
    helices 2 and 3 are shorther than helices 1 and 4
    automatically mapped to Pfam PF04011
  8. 2318372a.29.10: MAST3 pre-PK domain-like [140482] (1 family) (S)
    this domain precedes the Protein Kinase domain in Microtubule-associated serine/threonine-protein kinase 3 (MAST3)
    automatically mapped to Pfam PF08926
  9. 2318380a.29.11: PA2201 N-terminal domain-like [140486] (1 family) (S)
  10. 2318387a.29.12: Nqo1C-terminal domain-like [140490] (2 families) (S)
    contains extra C-terminal helix that caps the bundle at one end and Fe4-S4 cluster at the other end
  11. 2318406a.29.13: Bacillus cereus metalloprotein-like [158430] (1 family) (S)
    Duplication: tandem repeat of two domains of this fold with similar sequences; binds a dimetal ion cluster between the repeats
    automatically mapped to Pfam PF11155
  12. 2318464a.29.14: Ta0600-like [158436] (1 family) (S)
    automatically mapped to Pfam PF03685
  13. 2318475a.29.15: DsbB-like [158442] (1 family) (S)
    contains an extra helix in a long loop between helices 3 and 4
    automatically mapped to Pfam PF02600
  14. 2318480a.29.16: IVS-encoded protein-like [158446] (1 family) (S)
    IVS: Intervening sequence with conserved ORF in eubacterial 23S rRNA genes; forms a homopentamer with a toroid-shaped structure containing a tapered central channel
    automatically mapped to Pfam PF05635
  15. 2318498a.29.17: YqcC-like [158452] (1 family) (S)
    automatically mapped to Pfam PF04287

More info for Fold a.29: Bromodomain-like

Timeline for Fold a.29: Bromodomain-like: