SCOPe 2.08: Domain d5ufxb_: 5ufx B:

Lineage for d5ufxb_ (5ufx B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d5ufxb_: 5ufx B: [348291]
   automated match to d3erta_
   complexed with 86y

Details for d5ufxb_

PDB Entry: 5ufx, 1.55 Å

PDB Description: estrogen receptor alpha ligand binding domain in complex with op1074

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d5ufxb_:

Sequence, based on SEQRES records:

>d5ufxb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld
ah

Sequence, based on observed residues (ATOM records):

>d5ufxb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfsmmglltnladrelvhminwakrvpgfv
dltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdml
latssrfrmmnlqgeefvclksiillnsgvytleekdhihrvldkitdtlihlmakaglt
lqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemldah

Timeline for d5ufxb_:

• d5ufxb_ first appeared in SCOPe 2.07