SCOPe 2.01: Domain d1qona_: 1qon A:

Lineage for d1qona_ (1qon A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)

6. Protein Acetylcholinesterase [53476] (5 species)

7. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [53481] (3 PDB entries)

8. Domain d1qona_: 1qon A: [34623]
   complexed with i40, so4

Details for d1qona_

PDB Entry: 1qon, 2.72 Å

PDB Description: ache from drosophila melanogaster complex with tacrine derivative 9- (3-iodobenzylamino)-1,2,3,4-tetrahydroacridine

PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d1qona_:

Sequence, based on SEQRES records:

>d1qona_ c.69.1.1 (A:) Acetylcholinesterase {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}
vidrlvvqtssgpvrgrsvtvqgrevhvytgipyakppvedlrfrkpvpaepwhgvldat
glsatcvqeryeyfpgfsgeeiwnpntnvsedclyinvwapakarlrhgrganggehpng
kqadtdhlihngnpqnttnglpiliwiygggfmtgsatldiynadimaavgnvivasfqy
rvgafgflhlapempsefaeeapgnvglwdqalairwlkdnahafggnpewmtlfgesag
sssvnaqlmspvtrglvkrgmmqsgtmnapwshmtsekaveigkalindcncnasmlktn
pahvmscmrsvdaktisvqqwnsysgilsfpsaptidgaflpadpmtlmktadlkdydil
mgnvrdegtyfllydfidyfdkddatalprdkyleimnnifgkatqaereaiifqytswe
gnpgyqnqqqigravgdhfftcptneyaqalaergasvhyyyfthrtstslwgewmgvlh
gdeieyffgqplnnslqyrpverelgkrmlsaviefaktgnpaqdgeewpnfskedpvyy
ifstddkieklargplaarcsfwndylpkvrsw

Sequence, based on observed residues (ATOM records):

>d1qona_ c.69.1.1 (A:) Acetylcholinesterase {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}
vidrlvvqtssgpvrgrsvtvqgrevhvytgipyakppvedlrfrkpvpaepwhgvldat
glsatcvqeryeyfpgfsgeeiwnpntnvsedclyinvwapanttnglpiliwiygggfm
tgsatldiynadimaavgnvivasfqyrvgafgflhlapempsefaeeapgnvglwdqal
airwlkdnahafggnpewmtlfgesagsssvnaqlmspvtrglvkrgmmqsgtmnapwsh
mtsekaveigkalindcncnasmlktnpahvmscmrsvdaktisvqqwnsysgilsfpsa
ptidgaflpadpmtlmktadlkdydilmgnvrdegtyfllydfidyfdkddatalprdky
leimnnifgkatqaereaiifqytswegnpgyqnqqqigravgdhfftcptneyaqalae
rgasvhyyyfthrtstslwgewmgvlhgdeieyffgqplnnslqyrpverelgkrmlsav
iefaktgnpaqdgeewpnfskedpvyyifstddkieklargplaarcsfwndylpkvrsw

Timeline for d1qona_:

• d1qona_ first appeared (with stable ids) in SCOP 1.55
  
• d1qona_ appears in SCOP 1.75
  
• d1qona_ appears in SCOPe 2.02
  
• d1qona_ appears in the current release, SCOPe 2.08