SCOPe 2.08: Domain d5o7ac1: 5o7a C:1-245

Lineage for d5o7ac1 (5o7a C:1-245)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.32: Tubulin nucleotide-binding domain-like [52489] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.32.1: Tubulin nucleotide-binding domain-like [52490] (2 families)
   automatically mapped to Pfam PF00091

5. Family c.32.1.1: Tubulin, GTPase domain [52491] (4 proteins)

6. Protein automated matches [226837] (9 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [226564] (136 PDB entries)

8. Domain d5o7ac1: 5o7a C:1-245 [336535]
   Other proteins in same PDB: d5o7aa2, d5o7ab2, d5o7ac2, d5o7ad2, d5o7ae_, d5o7af1, d5o7af2
   automated match to d4ihja1
   complexed with 9n5, acp, gdp, gtp, mg

Details for d5o7ac1

PDB Entry: 5o7a, 2.5 Å

PDB Description: quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin

PDB Compounds: (C:) Tubulin alpha-1B chain

SCOPe Domain Sequences for d5o7ac1:

Sequence; same for both SEQRES and ATOM records:

>d5o7ac1 c.32.1.1 (C:1-245) automated matches {Cow (Bos taurus) [TaxId: 9913]}
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfd

Timeline for d5o7ac1:

• d5o7ac1 first appeared in SCOPe 2.06
  
• d5o7ac1 appears in SCOPe 2.07