SCOPe 2.06: Domain d3uelc_: 3uel C:

Lineage for d3uelc_ (3uel C:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.50: Macro domain-like [52948] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest

4. Superfamily c.50.1: Macro domain-like [52949] (4 families)

5. Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like [310642] (2 proteins)
   Pfam PF05028
   Contains N- and C-terminal extensions to macrodomain, including Tyr clasp, discussed in PubMed 22609859

6. Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain [310785] (3 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [311041] (2 PDB entries)

8. Domain d3uelc_: 3uel C: [306653]
   automated match to d3ueka_
   complexed with a1r

Details for d3uelc_

PDB Entry: 3uel, 3 Å

PDB Description: Crystal structure of the catalytic domain of rat poly (ADP-ribose) glycohydrolase bound to ADP-HPD

PDB Compounds: (C:) Poly(ADP-ribose) glycohydrolase

SCOPe Domain Sequences for d3uelc_:

Sequence; same for both SEQRES and ATOM records:

>d3uelc_ c.50.1.3 (C:) Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
yvppnlppdkkwlgtpieemrkmprcgvrlpllrpsashtvtvrvdllragevpkpfpth
ykdlwdnkhvkmpcseqnlypvedengertagsrweliqtallnkftrpqnlkdailkyn
vayskkwdftalvdfwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllkqkmnh
svtmsqeqiasllanaffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfc
yfrrvtekkptglvtftrqsledfpewercdkpltrlhvtyegtiegngrgmlqvdfanr
fvgggvtgaglvqeeirflinpelivsrlftevldhnecliitgteqyseytgyaetyrw
arshedgsekddwqrccteivaidalhfrryldqfvpekvrrelnkaycgflrpgvppen
lsavatgnwgcgafggdarlkaliqllaaaaaerdvvyftfgdselmrdiysmhtflter
klnvgkvyrlllryyreecrdcsspgpdtklypfiyhaaes

Timeline for d3uelc_:

• d3uelc_ is new in SCOPe 2.06-stable
  
• d3uelc_ appears in SCOPe 2.07
  
• d3uelc_ appears in the current release, SCOPe 2.08