SCOPe 2.06: Protein: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain

Lineage for Protein: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain

Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.50: Macro domain-like [52948] (1 superfamily)
3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest
Superfamily c.50.1: Macro domain-like [52949] (4 families)

Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like [310642] (2 proteins)
Pfam PF05028
Contains N- and C-terminal extensions to macrodomain, including Tyr clasp, discussed in PubMed 22609859

Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain [310785] (3 species)

Species:

Homo sapiens [TaxId:9606] [324080] (1 PDB entry)
- Domain for 5lhb:
  - Domain d5lhba_: 5lhb A: [324081]
    automated match to d4fc2d_
    complexed with 6wj, dms, so4
Mouse (Mus musculus) [TaxId:10090] [311376] (7 PDB entries)
1. Domains for 4fc2:
  1. Domain d4fc2a_: 4fc2 A: [307353]
    automated match to d3ueka_
    complexed with so4
  2. Domain d4fc2b_: 4fc2 B: [307354]
    automated match to d3ueka_
    complexed with so4
  3. Domain d4fc2c_: 4fc2 C: [307355]
    automated match to d3ueka_
    complexed with so4
  4. Domain d4fc2d_: 4fc2 D: [307356]
    automated match to d3ueka_
    complexed with so4
2. Domain for 4n9y:
  - Domain d4n9ya_: 4n9y A: [307754]
    automated match to d3ueka_
    complexed with so4, v3l; mutant
3. Domains for 4n9z:
  1. Domain d4n9za_: 4n9z A: [307755]
    automated match to d3ueka_
    complexed with so4, v3l; mutant
  2. Domain d4n9zb_: 4n9z B: [307756]
    automated match to d3ueka_
    complexed with so4, v3l; mutant
4. Domains for 4na0:
  1. Domain d4na0a_: 4na0 A: [307757]
    automated match to d3ueka_
    complexed with ar6, iod
  2. Domain d4na0b_: 4na0 B: [307758]
    automated match to d3ueka_
    complexed with ar6, iod
  3. Domain d4na0c_: 4na0 C: [307759]
    automated match to d3ueka_
    complexed with ar6, iod
5. Domains for 4na4:
  1. Domain d4na4a_: 4na4 A: [307760]
    automated match to d3ueka_
    complexed with a1r, iod
  2. Domain d4na4b_: 4na4 B: [307761]
    automated match to d3ueka_
    complexed with a1r, iod
  3. Domain d4na4c_: 4na4 C: [307762]
    automated match to d3ueka_
    complexed with a1r, iod
6. Domain for 4na5:
  - Domain d4na5a_: 4na5 A: [307763]
    automated match to d3ueka_
    complexed with so4; mutant
7. Domains for 4na6:
  1. Domain d4na6a_: 4na6 A: [307764]
    automated match to d3ueka_
    complexed with so4; mutant
  2. Domain d4na6b_: 4na6 B: [307765]
    automated match to d3ueka_
    complexed with so4; mutant
Norway rat (Rattus norvegicus) [TaxId:10116] [311041] (2 PDB entries)
1. Domain for 3uek:
  - Domain d3ueka_: 3uek A: [306650]
2. Domains for 3uel:
  1. Domain d3uela_: 3uel A: [306651]
    automated match to d3ueka_
    complexed with a1r
  2. Domain d3uelb_: 3uel B: [306652]
    automated match to d3ueka_
    complexed with a1r
  3. Domain d3uelc_: 3uel C: [306653]
    automated match to d3ueka_
    complexed with a1r

More info for Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like

Timeline for Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like:

Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like is new in SCOPe 2.06-stable
Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like appears in SCOPe 2.07
Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like appears in the current release, SCOPe 2.08