SCOPe 2.08: Domain d2ckoa_: 2cko A:

Lineage for d2ckoa_ (2cko A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.8: Choline kinase [90040] (2 proteins)
   Pfam PF02958

6. Protein Choline kinase [90041] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [311002] (13 PDB entries)

8. Domain d2ckoa_: 2cko A: [303670]
   complexed with dtt

Details for d2ckoa_

PDB Entry: 2cko, 2.15 Å

PDB Description: crystal structure of human choline kinase alpha 2

PDB Compounds: (A:) choline kinase alpha

SCOPe Domain Sequences for d2ckoa_:

Sequence, based on SEQRES records:

>d2ckoa_ d.144.1.8 (A:) Choline kinase {Human (Homo sapiens) [TaxId: 9606]}
rrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgdeprkvllrl
ygailqvgaeamvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdis
aeiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlple
lenlrsllestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdign
hfcewmydysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeem
llevnrfalashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

Sequence, based on observed residues (ATOM records):

>d2ckoa_ d.144.1.8 (A:) Choline kinase {Human (Homo sapiens) [TaxId: 9606]}
rrraylwckeflpgawrglredefhisvirggsnmlfqcslpdttatlgdeprkvllrly
gaimvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisaeiaekma
tfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplelenlrsll
estpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignhfcewmyd
ysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeemllevnrfa
lashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

Timeline for d2ckoa_:

• d2ckoa_ first appeared in SCOPe 2.06
  
• d2ckoa_ appears in SCOPe 2.07