PDB entry 2cko

View 2cko on RCSB PDB site
Description: crystal structure of human choline kinase alpha 2
Class: transferase
Keywords: kinase, transferase, choline kinase, phosphatydilcholine, alternative splicing
Deposited on 2006-04-20, released 2006-10-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.204
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: choline kinase alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35790 (Start-389)
      • conflict (152)
      • conflict (354)
    Domains in SCOPe 2.08: d2ckoa_
  • Chain 'B':
    Compound: choline kinase alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35790 (107-389)
      • conflict (152)
      • conflict (354)
    Domains in SCOPe 2.08: d2ckob_
  • Heterogens: DTT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ckoA (A:)
gqqpplalppppplplplplpqppppqppadeqpeprtrrraylwckeflpgawrglred
efhisvirgglsnmlfqcslpdttatlgdeprkvllrlygailqvgaeamvlesvmfail
aerslgpklygifpqgrleqfipsrrldteelslpdisaeiaekmatfhgmkmpfnkepk
wlfgtmekylkevlrikfteesrikklhkllsynlplelenlrsllestpspvvfchndc
qegnilllegrensekqklmlidfeyssynyrgfdignhfcewmydysyekypffranir
kyptkkqqlhfissylpafqndfenlsteeksiikeemllevnrfalashflwglwsivq
akissiefgymdyaqarfdayfhqkrklgv

    Sequence, based on observed residues (ATOM records): (download) 
    >2ckoA (A:)
rrraylwckeflpgawrglredefhisvirggsnmlfqcslpdttatlgdeprkvllrly
gaimvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisaeiaekma
tfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplelenlrsll
estpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignhfcewmyd
ysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeemllevnrfa
lashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ckoB (B:)
gqqpplalppppplplplplpqppppqppadeqpeprtrrraylwckeflpgawrglred
efhisvirgglsnmlfqcslpdttatlgdeprkvllrlygailqvgaeamvlesvmfail
aerslgpklygifpqgrleqfipsrrldteelslpdisaeiaekmatfhgmkmpfnkepk
wlfgtmekylkevlrikfteesrikklhkllsynlplelenlrsllestpspvvfchndc
qegnilllegrensekqklmlidfeyssynyrgfdignhfcewmydysyekypffranir
kyptkkqqlhfissylpafqndfenlsteeksiikeemllevnrfalashflwglwsivq
akissiefgymdyaqarfdayfhqkrklgv

    Sequence, based on observed residues (ATOM records): (download) 
    >2ckoB (B:)
trrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgdeprkvllr
lygeamvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisaeiaek
matfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplelenlrs
llestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignhfcewm
ydysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeemllevnr
falashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv