SCOPe 2.07: Domain d4zmah_: 4zma H:

Lineage for d4zmah_ (4zma H:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (89 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d4zmah_: 4zma H: [280194]
   Other proteins in same PDB: d4zmal1, d4zmal2, d4zmal3, d4zmat1, d4zmat2
   automated match to d4jzeh_
   complexed with 0z6, bgc, ca, cac, fuc

Details for d4zmah_

PDB Entry: 4zma, 2.3 Å

PDB Description: crystal structure of a fviia-trypsin chimera (st) in complex with soluble tissue factor

PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d4zmah_:

Sequence, based on SEQRES records:

>d4zmah_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdceasspgkiteymfcagysdgsk
dsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprp
gvllrapfp

Sequence, based on observed residues (ATOM records):

>d4zmah_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdceasgkiteymfcagysdgskds
ckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprpgv
llrapfp

Timeline for d4zmah_:

• d4zmah_ first appeared in SCOPe 2.05
  
• d4zmah_ appears in SCOPe 2.06
  
• d4zmah_ appears in the current release, SCOPe 2.08