SCOPe 2.05: Domain d4uh6a_: 4uh6 A:

Lineage for d4uh6a_ (4uh6 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187302] (13 PDB entries)

8. Domain d4uh6a_: 4uh6 A: [274947]
   automated match to d3hsob_
   complexed with cl, h4b, hem, q1t, zn; mutant

Details for d4uh6a_

PDB Entry: 4uh6, 1.98 Å

PDB Description: structure of human nnos r354a g357d mutant heme domain in complex with 3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)-5-( methyl(2-(methylamino)ethyl)amino)benzonitrile

PDB Compounds: (A:) Nitric oxide synthase, brain

SCOPe Domain Sequences for d4uh6a_:

Sequence, based on SEQRES records:

>d4uh6a_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cprflkvknwetevvltdtlhlkstletgcteyicmgsimhpsqharrpedvatkdqlfp
lakefidqyyssikrfgskahmerleevnkeidttstyqlkdteliygakhawrnasrcv
griqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwn
sqliryagykqpdgstlgdpanvqfteiciqqgwkpprgrfdvlplllqangndpelfqi
ppelvlevpirhpkfewfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvr
dycdnsrynileevakkmnldmrktsslwkdqalveiniavlysfqsdkvtivdhhsate
sfikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw
k

Sequence, based on observed residues (ATOM records):

>d4uh6a_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cprflkvknwetevvltdtlhlkstletgcteyicmgsimhpdvatkdqlfplakefidq
yyssikrfgskahmerleevnkeidttstyqlkdteliygakhawrnasrcvgriqwskl
qvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliryag
ykqpdgstlgdpanvqfteiciqqgwkpprgrfdvlplllqangndpelfqippelvlev
pirhpkfewfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdnsry
nileevakkmnldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhmen
eyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwk

Timeline for d4uh6a_:

• d4uh6a_ is new in SCOPe 2.05-stable
  
• d4uh6a_ appears in SCOPe 2.06
  
• d4uh6a_ appears in the current release, SCOPe 2.08