SCOPe 2.07: Domain d4tyba_: 4tyb A:

Lineage for d4tyba_ (4tyb A:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)

8. Domain d4tyba_: 4tyb A: [272995]
   automated match to d3qgda_
   complexed with 3b1

Details for d4tyba_

PDB Entry: 4tyb, 2.93 Å

PDB Description: an ligand-observed mass spectrometry-based approach integrated into the fragment based lead discovery pipeline

PDB Compounds: (A:) Polyprotein

SCOPe Domain Sequences for d4tyba_:

Sequence, based on SEQRES records:

>d4tyba_ e.8.1.4 (A:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasqldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d4tyba_ e.8.1.4 (A:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpnsllrhhnmvyattsrsaglrqkkvtfdrlqvlddhyr
dvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihsvwkd
lledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqvvmgss
ygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdlapear
qaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacraaklqd
ctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydlelitscssnv
svahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilmthff
sillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrvasclr
klgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipsgwfvagysg
gdiyh

Timeline for d4tyba_:

• d4tyba_ first appeared in SCOPe 2.05
  
• d4tyba_ appears in SCOPe 2.06
  
• d4tyba_ appears in the current release, SCOPe 2.08