Lineage for d3qgda_ (3qgd A:)
- Root: SCOPe 2.07
Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds) 
Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all membersSuperfamily e.8.1: DNA/RNA polymerases [56672] (8 families) 
"palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins) Protein Viral RNA polymerase [56695] (17 species) Species Hepatitis C virus [TaxId:11103] [56697] (72 PDB entries) 
Domain d3qgda_: 3qgd A: [184371]
automated match to d1nb4a_
protein/RNA complex; complexed with 23e, 26s, so4
Details for d3qgda_
PDB Entry: 3qgd (more details), 2.6 Å
PDB Description: Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide
PDB Compounds: (A:) RNA-directed RNA polymeraseSCOPe Domain Sequences for d3qgda_:
Sequence, based on SEQRES records: (download)
>d3qgda_ e.8.1.4 (A:) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeetklpinalsnsllrhhnlvyattsrsaslrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsarskfgygakdvrnlsskavnhir
svwkdlledtetpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqavmgssygfqyspgqrveflvnawkakkcpmgfaydtrcfdstvtendirveesiy
qccdlapearqairslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkaa
aacraaklqdctmlvcgddlvvicesagtqedeaslrafteamtrysappgdppkpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiiqrlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavrtklkltpip
aasqldlsswfvagysggdiyhslsr
Sequence, based on observed residues (ATOM records): (download)
>d3qgda_ e.8.1.4 (A:) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcrsaslrqkkvtfdrlqvlddhyrdvlkemkakastvkakllsveea
ckltpphsarskfgygakdvrnlsskavnhirsvwkdlledtetpidttimaknevfcvq
pekggrkparlivfpdlgvrvcekmalydvvstlpqavmgssygfqyspgqrveflvnaw
kakkcpmgfaydtrcfdstvtendirveesiyqccdlapearqairslterlyiggpltn
skgqncgyrrcrasgvlttscgntltcylkaaaacraaklqdctmlvcgddlvvicesag
tqedeaslrafteamtrysappgdppkpeydlelitscssnvsvahdasgkrvyyltrdp
ttplaraawetarhtpvnswlgniimyaptlwarmilmthffsillaqeqlekaldcqiy
gacysiepldlpqiiqrlhglsafslhsyspgeinrvasclrklgvpplrvwrhrarsvr
arllsqggraatcgkylfnwavrtklkltpipaasqldlsswfvagysggdiyhslsr
SCOPe Domain Coordinates for d3qgda_:
Click to download the PDB-style file with coordinates for d3qgda_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d3qgda_:
- d3qgda_ first appeared in SCOPe 2.01
- d3qgda_ appears in SCOPe 2.06
- d3qgda_ appears in the current release, SCOPe 2.08
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