SCOPe 2.07: Domain d4wmra1: 4wmr A:173-321

Lineage for d4wmra1 (4wmr A:173-321)

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (88 PDB entries)

8. Domain d4wmra1: 4wmr A:173-321 [272411]
   Other proteins in same PDB: d4wmra2
   automated match to d2kbwa_
   complexed with 865, pop, zn

Details for d4wmra1

PDB Entry: 4wmr, 1.7 Å

PDB Description: structure of mcl1 bound to brd inhibitor ligand 1 at 1.7a

PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d4wmra1:

Sequence; same for both SEQRES and ATOM records:

>d4wmra1 f.1.4.1 (A:173-321) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgml
rkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplae
sitdvlvrtkrdwlvkqrgwdgfveffhv

Timeline for d4wmra1:

• d4wmra1 first appeared in SCOPe 2.05, called d4wmra_
  
• d4wmra1 appears in SCOPe 2.06
  
• d4wmra1 appears in the current release, SCOPe 2.08