SCOP 1.63: Domain d1foeg2: 1foe G:1240-1401

Lineage for d1foeg2 (1foe G:1240-1401)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.55: PH domain-like [50728] (1 superfamily)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (6 families)

5. Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (14 proteins)

6. Protein GEF of TIAM1 (T-Lymphoma invasion and metastasis indusing protein 1) [50745] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [50746] (1 PDB entry)

8. Domain d1foeg2: 1foe G:1240-1401 [26972]
   Other proteins in same PDB: d1foea1, d1foeb_, d1foec1, d1foed_, d1foee1, d1foef_, d1foeg1, d1foeh_
   complexed with so4; mutant

Details for d1foeg2

PDB Entry: 1foe, 2.8 Å

PDB Description: crystal structure of rac1 in complex with the guanine nucleotide exchange region of tiam1

SCOP Domain Sequences for d1foeg2:

Sequence; same for both SEQRES and ATOM records:

>d1foeg2 b.55.1.1 (G:1240-1401) GEF of TIAM1 (T-Lymphoma invasion and metastasis indusing protein 1) {Mouse (Mus musculus)}
efgavfdqliaeqtgekkevadlsmgdlllhtsviwlnppaslgkwkkepelaafvfkta
vvlvykdgskqkkklvgshrlsiyeewdpfrfrhmiptealqvralpsadaeanavceiv
hvksesegrpervfhlccsspesrkdflksvhsilrdkhrrq

Timeline for d1foeg2:

• d1foeg2 first appeared (with stable ids) in SCOP 1.55
  
• d1foeg2 appears in SCOP 1.61
  
• d1foeg2 appears in SCOP 1.65
  
• d1foeg2 appears in the current release, SCOPe 2.08