SCOPe 2.05: Domain d4nrub_: 4nru B:

Lineage for d4nrub_ (4nru B:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (26 species)
   not a true protein

7. Species Murine norovirus 1 [TaxId:223997] [189982] (8 PDB entries)

8. Domain d4nrub_: 4nru B: [263215]
   automated match to d1sh0b_
   protein/RNA complex; complexed with 2ng, mg

Details for d4nrub_

PDB Entry: 4nru, 2.3 Å

PDB Description: Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative

PDB Compounds: (B:) RNA dependent RNA polymerase

SCOPe Domain Sequences for d4nrub_:

Sequence, based on SEQRES records:

>d4nrub_ e.8.1.4 (B:) automated matches {Murine norovirus 1 [TaxId: 223997]}
prpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqqv
mrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgyp
yhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikkr
llwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmdad
ytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsgc
pcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytmal
rrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgpn
hqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgiemvvprhrsvl
rwvrfg

Sequence, based on observed residues (ATOM records):

>d4nrub_ e.8.1.4 (B:) automated matches {Murine norovirus 1 [TaxId: 223997]}
prpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqqv
mrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgyp
yhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikkr
llwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmdad
ytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsgc
pcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytmal
rrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgpn
hqnpfetlpghqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgvvprhrsvlrwvr
fg

Timeline for d4nrub_:

• d4nrub_ is new in SCOPe 2.05-stable
  
• d4nrub_ appears in SCOPe 2.06
  
• d4nrub_ appears in the current release, SCOPe 2.08