SCOPe 2.06: Family b.1.29.1: Alpha-macroglobulin receptor domain

Lineage for Family b.1.29.1: Alpha-macroglobulin receptor domain

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.29: Macroglobulin [254121] (8 families)
   C3 MG domains possibly arose by gene duplication according to PubMed 16177781; PubMed 17608619; possibly related to immunoglobulins according to Pfam clan annotations

5. Family b.1.29.1: Alpha-macroglobulin receptor domain [254148] (4 proteins)
   Pfam PF07677

Proteins:

1. alpha-1-macroglobulin [254335] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [254766] (1 PDB entry)

2. alpha-2-macroglobulin [254336] (2 species)

   1. Species Cow (Bos taurus) [TaxId:9913] [254767] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [254768] (1 PDB entry)

3. Complement C3 MG8 [254362] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [254795] (1 PDB entry)

4. Complement C5 MG8 [254363] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [254796] (1 PDB entry)

More info for Family b.1.29.1: Alpha-macroglobulin receptor domain

Timeline for Family b.1.29.1: Alpha-macroglobulin receptor domain:

• Family b.1.29.1: Alpha-macroglobulin receptor domain first appeared in SCOPe 2.04
  
• Family b.1.29.1: Alpha-macroglobulin receptor domain appears in SCOPe 2.05
  
• Family b.1.29.1: Alpha-macroglobulin receptor domain appears in SCOPe 2.07
  
• Family b.1.29.1: Alpha-macroglobulin receptor domain appears in the current release, SCOPe 2.08