SCOPe 2.06: Superfamily b.1.29: Macroglobulin

Lineage for Superfamily b.1.29: Macroglobulin

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.29: Macroglobulin [254121] (8 families)
   C3 MG domains possibly arose by gene duplication according to PubMed 16177781; PubMed 17608619; possibly related to immunoglobulins according to Pfam clan annotations

Families:

1. b.1.29.1: Alpha-macroglobulin receptor domain [254148] (4 proteins)
   Pfam PF07677

2. b.1.29.2: Complement C3 MG1-like [254155] (2 proteins)

3. b.1.29.3: Complement C3 MG2-like [254156] (3 proteins)
   Pfam PF01835

4. b.1.29.4: Complement C3 MG3-like [254157] (2 proteins)

5. b.1.29.5: Complement C3 MG4-like [254158] (2 proteins)

6. b.1.29.6: Complement C3 MG5-like [254159] (2 proteins)
   Pfam PF07703

7. b.1.29.7: Complement C3 MG6-like [254160] (2 proteins)

8. b.1.29.8: Complement C3 MG7-like [254161] (2 proteins)

More info for Superfamily b.1.29: Macroglobulin

Timeline for Superfamily b.1.29: Macroglobulin:

• Superfamily b.1.29: Macroglobulin first appeared in SCOPe 2.04
  
• Superfamily b.1.29: Macroglobulin appears in SCOPe 2.05
  
• Superfamily b.1.29: Macroglobulin appears in SCOPe 2.07
  
• Superfamily b.1.29: Macroglobulin appears in the current release, SCOPe 2.08