SCOPe 2.06: Domain d4khmb_: 4khm B:

Lineage for d4khmb_ (4khm B:)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein Viral RNA polymerase [56695] (18 species)

7. Species Hepatitis c virus subtype 1a [TaxId:31646] [189928] (4 PDB entries)

8. Domain d4khmb_: 4khm B: [197206]
   automated match to d3gnwb_
   protein/RNA complex; complexed with 1pv, so4

Details for d4khmb_

PDB Entry: 4khm, 1.7 Å

PDB Description: hcv ns5b gt1a with gsk5852

PDB Compounds: (B:) HCV Polymerase

SCOPe Domain Sequences for d4khmb_:

Sequence; same for both SEQRES and ATOM records:

>d4khmb_ e.8.1.4 (B:) Viral RNA polymerase {Hepatitis c virus subtype 1a [TaxId: 31646]}
smsyswtgalvtpcaaeeqklpinalsnsllrhhnlvysttsrsacqrqkkvtfdrlqvl
dshyqdvlkevkaaaskvkanllsveeacsltpphsakskygygakdvrshasravahin
svwkdlledsvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
klplavmgssygfqyspgqrveflvqawkskktpmgfsydtrcfdstvtesdirteeaiy
qccdldpqarvaikslterlyvggpltnsrgencgyrrcrasgvlttscgntltcyikar
aacraaglqdctmlvcgddlvvicesagvqedaaslrafteamtrysappgdppqpeydl
elitscssnvsvahdgagkrvyyltrdpttplaraawetarhtpvnswlgniimfaptlw
armilmthffsvliardqleqaldceiygacysiepldlppiiqrlhglsafslhsyspg
einrvaaclrklgvpplrawrhrarsvrarllsrggraaicgkylfnwavrtklkltpia
aagqlalsgwftagysggdiyh

Timeline for d4khmb_:

• d4khmb_ first appeared in SCOPe 2.02
  
• d4khmb_ appears in SCOPe 2.05
  
• d4khmb_ appears in SCOPe 2.07
  
• d4khmb_ appears in the current release, SCOPe 2.08