Lineage for Family e.8.1.4: RNA-dependent RNA-polymerase

  1. Root: SCOPe 2.06
  2. 2243857Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)
  3. 2246832Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2246833Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2247714Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 protein domains)

Protein Domains:

  1. 2247715Reovirus polymerase lambda3 [82841] (1 species)
    contains additional N-terminal domain (res. 1-380) and C-terminal "bracelet" domain (res. 891-1267)
  2. 2247722Viral RNA polymerase [56695] (18 species)
    1. 2247723Species Avian infectious bursal disease virus [TaxId:10995] [160955] (1 PDB entry)
      Uniprot Q9Q6Q5 31-804
    2. 2247725Species Bovine viral diarrhea virus [TaxId:11099] [103401] (3 PDB entries)
    3. 2247732Species Foot-and-mouth disease virus - type c [TaxId:12116] [187085] (9 PDB entries)
    4. 2247742Species Foot-and-mouth disease virus [TaxId:12110] [111302] (7 PDB entries)
      Uniprot Q9QCE4 1858-2327
    5. 2247752Species Hepatitis c virus genotype 2a (isolate jfh-1) [TaxId:356411] [331359] (1 PDB entry)
    6. 2247754Species Hepatitis C virus isolate bk [TaxId:11105] [195056] (4 PDB entries)
    7. 2247763Species Hepatitis c virus isolate [TaxId:420174] [188905] (22 PDB entries)
    8. 2247806Species Hepatitis c virus subtype 1a [TaxId:31646] [189928] (4 PDB entries)
    9. 2247813Species Hepatitis C virus [TaxId:11103] [56697] (72 PDB entries)
    10. 2247950Species Hepatitis C virus [TaxId:356411] [193797] (2 PDB entries)
    11. 2247953Species Human poliovirus 1 [TaxId:12081] [256393] (8 PDB entries)
    12. 2247962Species Human rhinovirus 14, HRV-14 [TaxId:12131] [111301] (2 PDB entries)
      Uniprot P03303 1720-2179
    13. 2247965Species Human rhinovirus 16 [TaxId:31708] [188024] (2 PDB entries)
    14. 2247973Species Human rhinovirus 16, HRV-16 [TaxId:31708] [111300] (2 PDB entries)
      Uniprot Q82122 1694-2153
    15. 2247978Species Human rhinovirus 1B, HRV-1B [TaxId:12129] [111299] (2 PDB entries)
      Uniprot P12916 1698-2157
    16. 2247981Species Norwalk virus [TaxId:11983] [103400] (8 PDB entries)
    17. 2247992Species Poliovirus type 1, strain Mahoney [TaxId:12080] [56696] (12 PDB entries)
      Uniprot P03300 1748-2208
    18. 2248024Species Rabbit hemorrhagic disease virus [TaxId:11976] [69882] (2 PDB entries)
  3. 2248029automated matches [190260] (29 species)
    not a true protein
    1. 2248030Species Bovine viral diarrhea virus [TaxId:11099] [255087] (1 PDB entry)
    2. 2248032Species Coxsackievirus b3 [TaxId:103903] [188493] (5 PDB entries)
    3. 2248038Species Coxsackievirus b3 [TaxId:12072] [271111] (10 PDB entries)
    4. 2248049Species Enterovirus d68 [TaxId:42789] [336371] (1 PDB entry)
    5. 2248051Species Foot-and-mouth disease virus [TaxId:12120] [272422] (2 PDB entries)
    6. 2248054Species Hepatitis B virus [TaxId:10407] [259720] (1 PDB entry)
    7. 2248056Species Hepatitis c virus (isolate 1) [TaxId:11104] [261697] (1 PDB entry)
    8. 2248058Species Hepatitis c virus genotype 1b (isolate bk) [TaxId:11105] [337979] (1 PDB entry)
    9. 2248061Species Hepatitis c virus genotype 1b (isolate con1) [TaxId:333284] [331357] (7 PDB entries)
    10. 2248076Species Hepatitis C virus isolate bk [TaxId:11105] [188687] (11 PDB entries)
    11. 2248099Species Hepatitis c virus isolate hc-j6 [TaxId:11113] [189608] (1 PDB entry)
    12. 2248101Species Hepatitis c virus isolate hc-j8 [TaxId:11115] [188981] (2 PDB entries)
    13. 2248106Species Hepatitis c virus isolate [TaxId:420174] [188851] (1 PDB entry)
    14. 2248109Species Hepatitis c virus jfh-1 [TaxId:356411] [189047] (3 PDB entries)
    15. 2248116Species Hepatitis c virus subtype 1a [TaxId:31646] [189338] (1 PDB entry)
    16. 2248120Species Hepatitis c virus subtype 1b [TaxId:31647] [187148] (4 PDB entries)
    17. 2248131Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)
    18. 2248224Species Hepatitis C virus [TaxId:11105] [188793] (3 PDB entries)
    19. 2248230Species Hepatitis C virus [TaxId:333284] [188792] (1 PDB entry)
    20. 2248232Species Hepatitis C virus [TaxId:356411] [189609] (1 PDB entry)
    21. 2248234Species Hepatitis C virus [TaxId:420174] [189885] (4 PDB entries)
    22. 2248242Species Human coxsackievirus B3 [TaxId:12072] [193138] (3 PDB entries)
    23. 2248255Species Human coxsackievirus [TaxId:12072] [188608] (1 PDB entry)
    24. 2248257Species Human enterovirus 71 [TaxId:39054] [189988] (4 PDB entries)
    25. 2248262Species Human poliovirus 1 [TaxId:12081] [193135] (16 PDB entries)
    26. 2248284Species Human rhinovirus a16 [TaxId:31708] [193142] (1 PDB entry)
    27. 2248286Species Murine norovirus 1 [TaxId:223997] [189982] (8 PDB entries)
    28. 2248314Species Murine norovirus [TaxId:223997] [226374] (2 PDB entries)
    29. 2248321Species Norwalk-like virus [TaxId:95340] [260334] (1 PDB entry)

More info for Family e.8.1.4: RNA-dependent RNA-polymerase

Timeline for Family e.8.1.4: RNA-dependent RNA-polymerase: