SCOPe 2.02: Domain d3erdb_: 3erd B:

Lineage for d3erdb_ (3erd B:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (58 PDB entries)
   Uniprot P03372 307-551

8. Domain d3erdb_: 3erd B: [19294]
   complex with diethylstilbestrol and a peptide
   complexed with acy, cl, des

Details for d3erdb_

PDB Entry: 3erd, 2.03 Å

PDB Description: human estrogen receptor alpha ligand-binding domain in complex with diethylstilbestrol and a glucocorticoid receptor interacting protein 1 nr box ii peptide

PDB Compounds: (B:) protein (estrogen receptor alpha)

SCOPe Domain Sequences for d3erdb_:

Sequence, based on SEQRES records:

>d3erdb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahrlh

Sequence, based on observed residues (ATOM records):

>d3erdb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfeekdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahrlh

Timeline for d3erdb_:

• d3erdb_ first appeared (with stable ids) in SCOP 1.55
  
• d3erdb_ appears in SCOPe 2.01
  
• d3erdb_ appears in SCOPe 2.03
  
• d3erdb_ appears in the current release, SCOPe 2.08