Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.02
  2. 1074916Class a: All alpha proteins [46456] (284 folds)
  3. 1097039Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 1097040Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 1097041Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)
  6. 1097125Protein Estrogen receptor alpha [48519] (1 species)
  7. 1097126Species Human (Homo sapiens) [TaxId:9606] [48520] (58 PDB entries)
    Uniprot P03372 307-551

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1a52:
    1. 1097214Domain d1a52a_: 1a52 A: [19296]
      complexed with au, est
    2. 1097215Domain d1a52b_: 1a52 B: [19297]
      complexed with au, est
  2. Domain(s) for 1ere:
    1. 1097231Domain d1erea_: 1ere A: [19300]
      complexed with est
    2. 1097232Domain d1ereb_: 1ere B: [19301]
      complexed with est
    3. 1097233Domain d1erec_: 1ere C: [19302]
      complexed with est
    4. 1097234Domain d1ered_: 1ere D: [19303]
      complexed with est
    5. 1097235Domain d1eree_: 1ere E: [19304]
      complexed with est
    6. 1097236Domain d1eref_: 1ere F: [19305]
      complexed with est
  3. Domain(s) for 1err:
    1. 1097221Domain d1erra_: 1err A: [19298]
      complexed with ral
    2. 1097222Domain d1errb_: 1err B: [19299]
      complexed with ral
  4. Domain(s) for 1g50:
    1. 1097237Domain d1g50a_: 1g50 A: [65149]
      complexed with est
    2. 1097238Domain d1g50b_: 1g50 B: [65150]
      complexed with est
    3. 1097239Domain d1g50c_: 1g50 C: [65151]
      complexed with est
  5. Domain(s) for 1gwq:
    1. 1097196Domain d1gwqa_: 1gwq A: [76366]
      complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
      protein/DNA complex; complexed with ztw
    2. 1097197Domain d1gwqb_: 1gwq B: [76367]
      complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
      protein/DNA complex; complexed with ztw
  6. Domain(s) for 1gwr:
    1. 1097198Domain d1gwra_: 1gwr A: [76368]
      complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
      protein/DNA complex; complexed with est
    2. 1097199Domain d1gwrb_: 1gwr B: [76369]
      complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
      protein/DNA complex; complexed with est
  7. Domain(s) for 1l2i:
    1. 1097145Domain d1l2ia_: 1l2i A: [73503]
      complexed with cl, etc
    2. 1097146Domain d1l2ib_: 1l2i B: [73504]
      complexed with cl, etc
  8. Domain(s) for 1pcg:
    1. 1097206Domain d1pcga_: 1pcg A: [94432]
      complexed with est
    2. 1097207Domain d1pcgb_: 1pcg B: [94433]
      complexed with est
  9. Domain(s) for 1qkt:
    • 1097186Domain d1qkta_: 1qkt A: [19295]
      complex with estradiol
      complexed with est; mutant
  10. Domain(s) for 1qku:
    1. 1097240Domain d1qkua_: 1qku A: [19306]
      complex with estradiol
      complexed with est
    2. 1097241Domain d1qkub_: 1qku B: [19307]
      complex with estradiol
      complexed with est
    3. 1097242Domain d1qkuc_: 1qku C: [19308]
      complex with estradiol
      complexed with est
  11. Domain(s) for 1r5k:
    1. 1097218Domain d1r5ka_: 1r5k A: [111706]
      protein/DNA complex; complexed with gw5
    2. 1097219Domain d1r5kb_: 1r5k B: [111707]
      protein/DNA complex; complexed with gw5
    3. 1097220Domain d1r5kc_: 1r5k C: [111708]
      protein/DNA complex; complexed with gw5
  12. Domain(s) for 1sj0:
  13. Domain(s) for 1uom:
  14. Domain(s) for 1x7e:
    1. 1097225Domain d1x7ea_: 1x7e A: [162037]
      automated match to d1g50a_
      complexed with 244
    2. 1097226Domain d1x7eb_: 1x7e B: [162038]
      automated match to d1g50a_
      complexed with 244
  15. Domain(s) for 1x7r:
  16. Domain(s) for 1xp1:
  17. Domain(s) for 1xp6:
  18. Domain(s) for 1xp9:
  19. Domain(s) for 1xpc:
  20. Domain(s) for 1yim:
  21. Domain(s) for 1yin:
  22. Domain(s) for 1zky:
    1. 1097178Domain d1zkya_: 1zky A: [162506]
      automated match to d1qkua_
      complexed with 689
    2. 1097179Domain d1zkyb_: 1zky B: [162507]
      automated match to d1qkua_
      complexed with 689
  23. Domain(s) for 2ayr:
  24. Domain(s) for 2b1v:
    1. 1097140Domain d2b1va_: 2b1v A: [162967]
      automated match to d1qkua_
      complexed with 458
    2. 1097141Domain d2b1vb_: 2b1v B: [162968]
      automated match to d1qkua_
      complexed with 458
  25. Domain(s) for 2b1z:
    1. 1097136Domain d2b1za_: 2b1z A: [162969]
      automated match to d1qkua_
      complexed with 17m
    2. 1097137Domain d2b1zb_: 2b1z B: [162970]
      automated match to d1qkua_
      complexed with 17m
  26. Domain(s) for 2b23:
    1. 1097180Domain d2b23a_: 2b23 A: [162971]
      automated match to d1qkua_
    2. 1097181Domain d2b23b_: 2b23 B: [162972]
      automated match to d1qkua_
  27. Domain(s) for 2fai:
    1. 1097171Domain d2faia_: 2fai A: [164311]
      automated match to d1qkua_
      complexed with 459
    2. 1097172Domain d2faib_: 2fai B: [164312]
      automated match to d1qkua_
      complexed with 459
  28. Domain(s) for 2g44:
    1. 1097212Domain d2g44a_: 2g44 A: [164578]
      automated match to d1qkua_
      complexed with t3o
    2. 1097213Domain d2g44b_: 2g44 B: [164579]
      automated match to d1qkua_
      complexed with t3o
  29. Domain(s) for 2g5o:
    1. 1097193Domain d2g5oa_: 2g5o A: [164583]
      automated match to d1qkua_
      complexed with drq
    2. 1097194Domain d2g5ob_: 2g5o B: [164584]
      automated match to d1qkua_
      complexed with drq
  30. Domain(s) for 2i0j:
    1. 1097227Domain d2i0ja_: 2i0j A: [165352]
      automated match to d1pcga_
      complexed with i0g
    2. 1097228Domain d2i0jb_: 2i0j B: [165353]
      automated match to d1pcga_
      complexed with i0g
    3. 1097229Domain d2i0jc_: 2i0j C: [165354]
      automated match to d1pcga_
      complexed with i0g
    4. 1097230Domain d2i0jd_: 2i0j D: [165355]
      automated match to d1pcga_
      complexed with i0g
  31. Domain(s) for 2iog:
  32. Domain(s) for 2iok:
    1. 1097216Domain d2ioka_: 2iok A: [147747]
      automated match to d1qkua_
      complexed with iok
    2. 1097217Domain d2iokb_: 2iok B: [147748]
      automated match to d1qkua_
      complexed with iok
  33. Domain(s) for 2ouz:
  34. Domain(s) for 2p15:
    1. 1097138Domain d2p15a_: 2p15 A: [166933]
      automated match to d1qkua_
      complexed with ezt
    2. 1097139Domain d2p15b_: 2p15 B: [166934]
      automated match to d1qkua_
      complexed with ezt
  35. Domain(s) for 2pog:
    1. 1097147Domain d2poga_: 2pog A: [149721]
      automated match to d1qkta_
      complexed with wst
    2. 1097148Domain d2pogb_: 2pog B: [161507]
      automated match to d1qkta_
      complexed with wst
  36. Domain(s) for 2q6j:
    1. 1097223Domain d2q6ja_: 2q6j A: [167457]
      automated match to d1qkua_
      complexed with a48
    2. 1097224Domain d2q6jb_: 2q6j B: [167458]
      automated match to d1qkua_
      complexed with a48
  37. Domain(s) for 2q70:
    1. 1097175Domain d2q70a_: 2q70 A: [150072]
      automated match to d1qkta_
      complexed with dc8
    2. 1097176Domain d2q70b_: 2q70 B: [161524]
      automated match to d1qkta_
      complexed with dc8
  38. Domain(s) for 2qa6:
    1. 1097204Domain d2qa6a_: 2qa6 A: [167488]
      automated match to d1qkua_
      complexed with kn2; mutant
    2. 1097205Domain d2qa6b_: 2qa6 B: [167489]
      automated match to d1qkua_
      complexed with kn2; mutant
  39. Domain(s) for 2qa8:
    1. 1097150Domain d2qa8a_: 2qa8 A: [167490]
      automated match to d1qkua_
      complexed with gen; mutant
    2. 1097151Domain d2qa8b_: 2qa8 B: [167491]
      automated match to d1qkua_
      complexed with gen; mutant
  40. Domain(s) for 2qab:
    1. 1097162Domain d2qaba_: 2qab A: [167492]
      automated match to d1qkua_
      complexed with ei1; mutant
    2. 1097163Domain d2qabb_: 2qab B: [167493]
      automated match to d1qkua_
      complexed with ei1; mutant
  41. Domain(s) for 2qe4:
    1. 1097202Domain d2qe4a_: 2qe4 A: [167557]
      automated match to d1qkta_
      protein/DNA complex; complexed with jj3
    2. 1097203Domain d2qe4b_: 2qe4 B: [167558]
      automated match to d1qkta_
      protein/DNA complex; complexed with jj3
  42. Domain(s) for 2qgt:
    1. 1097173Domain d2qgta_: 2qgt A: [167573]
      automated match to d1qkua_
      complexed with eed
    2. 1097174Domain d2qgtb_: 2qgt B: [167574]
      automated match to d1qkua_
      complexed with eed
  43. Domain(s) for 2qgw:
    1. 1097200Domain d2qgwa_: 2qgw A: [167585]
      automated match to d1qkua_
      complexed with ees
    2. 1097201Domain d2qgwb_: 2qgw B: [167586]
      automated match to d1qkua_
      complexed with ees
  44. Domain(s) for 2qh6:
    1. 1097210Domain d2qh6a_: 2qh6 A: [167591]
      automated match to d1qkua_
      complexed with ode
    2. 1097211Domain d2qh6b_: 2qh6 B: [167592]
      automated match to d1qkua_
      complexed with ode
  45. Domain(s) for 2qr9:
    1. 1097168Domain d2qr9a_: 2qr9 A: [167777]
      automated match to d1qkua_
      protein/DNA complex; complexed with hz3
    2. 1097169Domain d2qr9b_: 2qr9 B: [167778]
      automated match to d1qkua_
      protein/DNA complex; complexed with hz3
  46. Domain(s) for 2qse:
    1. 1097132Domain d2qsea_: 2qse A: [167792]
      automated match to d1qkua_
      protein/DNA complex; complexed with 1hp
    2. 1097133Domain d2qseb_: 2qse B: [167793]
      automated match to d1qkua_
      protein/DNA complex; complexed with 1hp
  47. Domain(s) for 2qxm:
    1. 1097208Domain d2qxma_: 2qxm A: [167870]
      automated match to d1qkua_
      protein/DNA complex; complexed with piq
    2. 1097209Domain d2qxmb_: 2qxm B: [167871]
      automated match to d1qkua_
      protein/DNA complex; complexed with piq
  48. Domain(s) for 2qxs:
    1. 1097130Domain d2qxsa_: 2qxs A: [167872]
      automated match to d1qkua_
      protein/DNA complex; complexed with ral; mutant
    2. 1097131Domain d2qxsb_: 2qxs B: [167873]
      automated match to d1qkua_
      protein/DNA complex; complexed with ral; mutant
  49. Domain(s) for 2qzo:
    1. 1097127Domain d2qzoa_: 2qzo A: [167892]
      automated match to d1qkua_
      protein/DNA complex; complexed with kn1
    2. 1097128Domain d2qzob_: 2qzo B: [167893]
      automated match to d1qkua_
      protein/DNA complex; complexed with kn1
  50. Domain(s) for 2r6w:
    1. 1097160Domain d2r6wa_: 2r6w A: [151621]
      automated match to d1qkta_
      protein/DNA complex; complexed with llb
    2. 1097161Domain d2r6wb_: 2r6w B: [151622]
      automated match to d1qkta_
      protein/DNA complex; complexed with llb
  51. Domain(s) for 2r6y:
    1. 1097158Domain d2r6ya_: 2r6y A: [151623]
      automated match to d1qkta_
      protein/DNA complex; complexed with llc
    2. 1097159Domain d2r6yb_: 2r6y B: [151624]
      automated match to d1qkta_
      protein/DNA complex; complexed with llc
  52. Domain(s) for 2yja:
  53. Domain(s) for 3dt3:
    1. 1097187Domain d3dt3a_: 3dt3 A: [157848]
      automated match to d1qkua_
      complexed with 369
    2. 1097188Domain d3dt3b_: 3dt3 B: [157849]
      automated match to d1qkua_
      complexed with 369
  54. Domain(s) for 3erd:
    1. 1097166Domain d3erda_: 3erd A: [19293]
      complex with diethylstilbestrol and a peptide
      complexed with acy, cl, des
    2. 1097167Domain d3erdb_: 3erd B: [19294]
      complex with diethylstilbestrol and a peptide
      complexed with acy, cl, des
  55. Domain(s) for 3ert:
    • 1097165Domain d3erta_: 3ert A: [19292]
      complex with 4-hydroxytamoxifen
      complexed with oht
  56. Domain(s) for 3os8:
    1. 1097152Domain d3os8a_: 3os8 A: [183253]
      automated match to d1qkua_
      complexed with kn0
    2. 1097153Domain d3os8b_: 3os8 B: [183254]
      automated match to d1qkua_
      complexed with kn0
    3. 1097154Domain d3os8c_: 3os8 C: [183255]
      automated match to d1qkua_
      complexed with kn0
    4. 1097155Domain d3os8d_: 3os8 D: [183256]
      automated match to d1qkua_
      complexed with kn0
  57. Domain(s) for 3os9:
    1. 1097182Domain d3os9a_: 3os9 A: [183257]
      automated match to d1qkua_
      complexed with kn1
    2. 1097183Domain d3os9b_: 3os9 B: [183258]
      automated match to d1qkua_
      complexed with kn1
    3. 1097184Domain d3os9c_: 3os9 C: [183259]
      automated match to d1qkua_
      complexed with kn1
    4. 1097185Domain d3os9d_: 3os9 D: [183260]
      automated match to d1qkua_
      complexed with kn1
  58. Domain(s) for 3osa:
    1. 1097189Domain d3osaa_: 3osa A: [183261]
      automated match to d1qkua_
      complexed with kn3
    2. 1097190Domain d3osab_: 3osa B: [183262]
      automated match to d1qkua_
      complexed with kn3
    3. 1097191Domain d3osac_: 3osa C: [183263]
      automated match to d1qkua_
      complexed with kn3
    4. 1097192Domain d3osad_: 3osa D: [183264]
      automated match to d1qkua_
      complexed with kn3

More info for Species Human (Homo sapiens) [TaxId:9606] from a.123.1.1 Estrogen receptor alpha

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.123.1.1 Estrogen receptor alpha: