SCOPe 2.01: Domain d3r4bb_: 3r4b B:

Lineage for d3r4bb_ (3r4b B:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein automated matches [190433] (10 species)
   not a true protein

7. Species Human immunodeficiency virus 1 [TaxId:11676] [187327] (21 PDB entries)

8. Domain d3r4bb_: 3r4b B: [184798]
   automated match to d1kzka_
   complexed with 74t, po4

Details for d3r4bb_

PDB Entry: 3r4b, 1.9 Å

PDB Description: crystal structure of wild-type hiv-1 protease in complex with tmc310911

PDB Compounds: (B:) hiv-1 protease

SCOPe Domain Sequences for d3r4bb_:

Sequence; same for both SEQRES and ATOM records:

>d3r4bb_ b.50.1.1 (B:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
pqitlwkrplvtiriggqlkealldtgaddtvleemnlpgkwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d3r4bb_:

• d3r4bb_ is new in SCOPe 2.01-stable
  
• d3r4bb_ appears in SCOPe 2.02
  
• d3r4bb_ appears in the current release, SCOPe 2.08