SCOPe 2.08: Domain d3oswa_: 3osw A:

Lineage for d3oswa_ (3osw A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d3oswa_: 3osw A: [183272]
   automated match to d1nyxa_
   complexed with pgo, xdi

Details for d3oswa_

PDB Entry: 3osw, 2.55 Å

PDB Description: crystal structure of ppargamma ligand binding domain in complex with tetrabromo-bisphenol a (tbbpa)

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3oswa_:

Sequence, based on SEQRES records:

>d3oswa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikf
khitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhe
iiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdl
aifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrq
ivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3oswa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkisk
evairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmn
kdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsg
drpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqv
ikktetdmslhpllqeiykdl

Timeline for d3oswa_:

• d3oswa_ first appeared in SCOPe 2.01
  
• d3oswa_ appears in SCOPe 2.07