SCOPe 2.02: Domain d3okja_: 3okj A:

Lineage for d3okja_ (3okj A:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

6. Protein Proteasome alpha subunit (non-catalytic) [56255] (6 species)
   contains an extension to the common fold at the N-terminus

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (37 PDB entries)
   The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)

8. Domain d3okja_: 3okj A: [183079]
   Other proteins in same PDB: d3okj1_, d3okj2_, d3okjd_, d3okjg_, d3okjh_, d3okji_, d3okjj_, d3okjk_, d3okjl_, d3okjm_, d3okjn_, d3okjr_, d3okju_, d3okjv_, d3okjw_, d3okjx_, d3okjy_, d3okjz_
   automated match to d1g65a_
   complexed with ep9

Details for d3okja_

PDB Entry: 3okj, 2.7 Å

PDB Description: alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition

PDB Compounds: (A:) Proteasome component Y7

SCOPe Domain Sequences for d3okja_:

Sequence; same for both SEQRES and ATOM records:

>d3okja_ d.153.1.4 (A:) Proteasome alpha subunit (non-catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mtdrysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamset
lskvslltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqe
atqsggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwn
deleledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrklts
qeindrleal

Timeline for d3okja_:

• d3okja_ first appeared in SCOPe 2.01
  
• d3okja_ appears in SCOPe 2.03
  
• d3okja_ appears in the current release, SCOPe 2.08