Lineage for Family d.153.1.4: Proteasome subunits

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1222614Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 1222615Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 1222781Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

Proteins:

  1. 1222782HslV (ClpQ) protease [56258] (4 species)
    dodecameric prokaryotic homologue of proteasome
    1. 1222783Species Bacillus subtilis [TaxId:1423] [160845] (2 PDB entries)
      Uniprot P39070 2-181
    2. 1222798Species Escherichia coli [TaxId:562] [56259] (8 PDB entries)
    3. 1222836Species Haemophilus influenzae [TaxId:727] [56260] (6 PDB entries)
    4. 1222879Species Thermotoga maritima [TaxId:2336] [90045] (1 PDB entry)
  2. 1222883Proteasome alpha subunit (non-catalytic) [56255] (6 species)
    contains an extension to the common fold at the N-terminus
    1. 1222884Species Archaeoglobus fulgidus [TaxId:2234] [90044] (2 PDB entries)
    2. 1222899Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (37 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 1223209Species Cow (Bos taurus) [TaxId:9913] [75568] (1 PDB entry)
    4. 1223224Species Mus musculus [TaxId:10090] [195927] (1 PDB entry)
    5. 1223226Species Rhodococcus erythropolis [TaxId:1833] [103314] (3 PDB entries)
    6. 1223248Species Thermoplasma acidophilum [TaxId:2303] [56256] (3 PDB entries)
  3. 1223291Proteasome beta subunit (catalytic) [56252] (5 species)
    1. 1223292Species Archaeoglobus fulgidus [TaxId:2234] [90043] (1 PDB entry)
    2. 1223300Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (34 PDB entries)
      The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
    3. 1223683Species Cow (Bos taurus) [TaxId:9913] [75567] (1 PDB entry)
    4. 1223698Species Rhodococcus erythropolis [TaxId:1833] [103313] (3 PDB entries)
    5. 1223720Species Thermoplasma acidophilum [TaxId:2303] [56253] (5 PDB entries)
  4. 1223777automated matches [190144] (8 species)
    not a true protein
    1. 1223778Species Bacillus anthracis [TaxId:198094] [189742] (1 PDB entry)
    2. 1223785Species Bacillus subtilis [TaxId:1423] [187296] (1 PDB entry)
    3. 1223798Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [187078] (20 PDB entries)
    4. 1223895Species Mus musculus [TaxId:10090] [195917] (2 PDB entries)
    5. 1223908Species Mycobacterium tuberculosis [TaxId:1773] [187707] (9 PDB entries)
    6. Species Saccharomyces cerevisiae [TaxId:4932] [192615] (3 PDB entries)
    7. 1224163Species Saccharomyces cerevisiae [TaxId:559292] [189752] (11 PDB entries)
    8. 1224185Species Thermoplasma acidophilum [TaxId:2303] [186869] (5 PDB entries)

More info for Family d.153.1.4: Proteasome subunits

Timeline for Family d.153.1.4: Proteasome subunits: