SCOPe 2.01: Domain d3klva_: 3klv A:

Lineage for d3klva_ (3klv A:)

1. Root: SCOPe 2.01

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein Viral RNA polymerase [56695] (14 species)

7. Species Foot-and-mouth disease virus [TaxId:12110] [111302] (14 PDB entries)
   Uniprot Q9QCE4 1858-2327

8. Domain d3klva_: 3klv A: [179431]
   automated match to d1u09a_
   protein/RNA complex; complexed with mg; mutant

Details for d3klva_

PDB Entry: 3klv, 2.6 Å

PDB Description: M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA

PDB Compounds: (A:) 3D polymerase

SCOPe Domain Sequences for d3klva_:

Sequence; same for both SEQRES and ATOM records:

>d3klva_ e.8.1.4 (A:) Viral RNA polymerase {Foot-and-mouth disease virus [TaxId: 12110]}
glivdtrdveervhvmrktklaptvahgvfnpefgpaalsnkdprlnegvvldevifskh
ksdtkmsaedkalfrrcaadyasrlhsvlgtanaplsiyeaikgvdgldamepdtapglp
walqgkrrgalidfengtvgpeveaalklmekreykfacqtflkdeirpmekvragktri
vdvlpvehilytrmmigrfcaqmhsnngpqigsavgcnpdvdwqrfgthfaqyrnvwdvd
ysafdanhcsdamnimfeevfrtefgfhpnaewilktlvntehayenkritveggipsgc
satsiintilnniyvlyalrrhyegveldtytmisygddivvasdydldfealkphfksl
gqtitpadksdkgfvlghsitdvtflkrhfhmdygtgfykpvmasktleailsfarrgti
qeklisvaglavhsgpdeyrrlfepfqglfeipsyrslylrwvnavcgdaaalehh

Timeline for d3klva_:

• d3klva_ is new in SCOPe 2.01-stable
  
• d3klva_ appears in SCOPe 2.02
  
• d3klva_ appears in the current release, SCOPe 2.08, called d3klva1