SCOPe 2.01: Domain d3iaka_: 3iak A:

Lineage for d3iaka_ (3iak A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (25 PDB entries)
   Uniprot Q08499 388-713

8. Domain d3iaka_: 3iak A: [178215]
   automated match to d1oyna_
   complexed with ev1, mg, zn

Details for d3iaka_

PDB Entry: 3iak, 2.8 Å

PDB Description: Crystal structure of human phosphodiesterase 4d (PDE4d) with papaverine.

PDB Compounds: (A:) cAMP-specific 3',5'-cyclic phosphodiesterase 4D

SCOPe Domain Sequences for d3iaka_:

Sequence; same for both SEQRES and ATOM records:

>d3iaka_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
mteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlit
ylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdh
pgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmv
idivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptk
plqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetw
adlvhpdaqdildtlednrewyqst

Timeline for d3iaka_:

• d3iaka_ is new in SCOPe 2.01-stable
  
• d3iaka_ appears in SCOPe 2.02
  
• d3iaka_ appears in the current release, SCOPe 2.08, called d3iaka1