SCOPe 2.07: Domain d2xi2b_: 2xi2 B:

Lineage for d2xi2b_ (2xi2 B:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus [TaxId:11103] [187048] (44 PDB entries)

8. Domain d2xi2b_: 2xi2 B: [170104]
   automated match to d1nb4a_
   complexed with so4

Details for d2xi2b_

PDB Entry: 2xi2, 1.8 Å

PDB Description: hcv-h77 ns5b apo polymerase

PDB Compounds: (B:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d2xi2b_:

Sequence, based on SEQRES records:

>d2xi2b_ e.8.1.4 (B:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsyswtgalvtpcaaeeqklpinalsnsllrhhnlvysttsrsacqrqkkvtfdrlqvl
dshyhdvlkevkaaaskvkanllsveeacsltpphsakskfgygakdvrcharkavahin
svwkdlledsvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
klplavmgssygfqyspgqrveflvqawkskktpmgfsydtrcfdstvtesdirteeaiy
qccdldpqarvaikslterlyvggpltnsrgencgyrrcrasgvlttscgntltcyikar
aacraaglqdctmlvcgddlvvicesagvqedaaslrafteamtrysappgdppqpeydl
elitscssnvsvahdgagkrvyyltrdpttplaraawetarhtpvnswlgniimfaptlw
armilmthffsvliardqleqalnceiygacysiepldlppiiqrlhglsafslhsyspg
einrvaaclrklgvpplrawrhrarsvrarllsrggraaicgkylfnwavrtklkltpia
aagrldlsgwftagysggdiyh

Sequence, based on observed residues (ATOM records):

>d2xi2b_ e.8.1.4 (B:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsyswtgalvtpcaaeeqklpinalsnsllrhhnlvysttsrsacqrqkkvtfdrlqvl
dshyhdvlkevkaaaskvkanllsveeacsltpphsakskfgygakdvrcharkavahin
svwkdlledsvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
klplavmgssygfqyspgqrveflvqawkskktpmgfsydtrcfdstvtesdirteeaiy
qccdldpqarvaikslterlyvggpltnsrgencgyrrcrasgvlttscgntltcyikar
aacraaglqdctmlvcgddlvvicesagvqedaaslrafteamtrysappgdppqpeydl
elitscssnvsvahdgagkrvyyltrdpttplaraawetarhtpvnswlgniimfaptlw
armilmthffsvliardqleqalnceiygacysiepldlppiiqrlhglsafslhsyspg
einrvaaclrklgvpplrawrhrarsvrarllsrggraaicgkylfnwavrtklkltpia
aagrlgwftagysggdiyh

Timeline for d2xi2b_:

• d2xi2b_ first appeared in SCOPe 2.01
  
• d2xi2b_ appears in SCOPe 2.06
  
• d2xi2b_ appears in the current release, SCOPe 2.08