SCOPe 2.01: Domain d2vgfa3: 2vgf A:440-573

Lineage for d2vgfa3 (2vgf A:440-573)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.49: Pyruvate kinase C-terminal domain-like [52934] (2 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145, strand 5 is antiparallel to the rest

4. Superfamily c.49.1: PK C-terminal domain-like [52935] (2 families)

5. Family c.49.1.1: Pyruvate kinase, C-terminal domain [52936] (1 protein)

6. Protein Pyruvate kinase, C-terminal domain [52937] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82431] (4 PDB entries)

8. Domain d2vgfa3: 2vgf A:440-573 [168554]
   Other proteins in same PDB: d2vgfa1, d2vgfa2, d2vgfb1, d2vgfb2, d2vgfc1, d2vgfc2, d2vgfd1, d2vgfd2
   complexed with fbp, k, mn, pga; mutant

Details for d2vgfa3

PDB Entry: 2vgf, 2.75 Å

PDB Description: human erythrocyte pyruvate kinase: t384m mutant

PDB Compounds: (A:) pyruvate kinase isozymes r/l

SCOPe Domain Sequences for d2vgfa3:

Sequence; same for both SEQRES and ATOM records:

>d2vgfa3 c.49.1.1 (A:440-573) Pyruvate kinase, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
elrraaplsrdptevtaigaveaafkccaaaiivltttgrsaqllsryrpraaviavtrs
aqaarqvhlcrgvfpllyreppeaiwaddvdrrvqfgiesgklrgflrvgdlvivvtgwr
pgsgytnimrvlsi

Timeline for d2vgfa3:

• d2vgfa3 is new in SCOPe 2.01-stable
  
• d2vgfa3 appears in SCOPe 2.02
  
• d2vgfa3 appears in the current release, SCOPe 2.08