SCOPe 2.08: Domain d2rb3c1: 2rb3 C:3-80

Lineage for d2rb3c1 (2rb3 C:3-80)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.64: Saposin-like [47861] (2 superfamilies)
   5 helices; folded leaf, closed

4. Superfamily a.64.1: Saposin [47862] (5 families)
   Lipid-binding can promote conformational changes and oligomerisation in some members

5. Family a.64.1.1: NKL-like [47863] (4 proteins)

6. Protein Saposin C [89077] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89078] (11 PDB entries)

8. Domain d2rb3c1: 2rb3 C:3-80 [168039]
   Other proteins in same PDB: d2rb3a2, d2rb3b2, d2rb3c2, d2rb3d2
   automated match to d2gtga1
   complexed with gol, so4

Details for d2rb3c1

PDB Entry: 2rb3, 2.1 Å

PDB Description: crystal structure of human saposin d

PDB Compounds: (C:) Proactivator polypeptide

SCOPe Domain Sequences for d2rb3c1:

Sequence; same for both SEQRES and ATOM records:

>d2rb3c1 a.64.1.1 (C:3-80) Saposin C {Human (Homo sapiens) [TaxId: 9606]}
gfcevckklvgyldrnleknstkqeilaalekgcsflpdpyqkqcdqfvaeyepvlieil
vevmdpsfvclkigacps

Timeline for d2rb3c1:

• d2rb3c1 first appeared in SCOPe 2.01, called d2rb3c_
  
• d2rb3c1 appears in SCOPe 2.07