SCOPe 2.01: Domain d2uyqa_: 2uyq A:

Lineage for d2uyqa_ (2uyq A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (58 families)

5. Family c.66.1.57: ML2640-like [159694] (2 proteins)
   Pfam PF02409; O-methyltransferase N-terminus (DUF142); most similar structure to the Leucine carboxy methyltransferase Ppm1 family

6. Protein automated matches [190566] (1 species)
   not a true protein

7. Species Mycobacterium leprae [TaxId:1769] [187556] (3 PDB entries)

8. Domain d2uyqa_: 2uyq A: [152322]
   automated match to d2ckda1
   complexed with sam

Details for d2uyqa_

PDB Entry: 2uyq, 1.8 Å

PDB Description: crystal structure of ml2640c from mycobacterium leprae in complex with s-adenosylmethionine

PDB Compounds: (A:) hypothetical protein ml2640

SCOPe Domain Sequences for d2uyqa_:

Sequence, based on SEQRES records:

>d2uyqa_ c.66.1.57 (A:) automated matches {Mycobacterium leprae [TaxId: 1769]}
vgttavmvaaaraaetdrpdalirdpyakllvtntgagalweamldpsmvakveaidaea
aamvehmrsyqavrtnffdtyfnnavidgirqfvilasgldsrayrldwptgttvyeidq
pkvlayksttlaehgvtptadrrevpidlrqdwppalrsagfdpsartawlaegllmylp
ataqdglfteigglsavgsriavetsplhgdewreqmqlrfrrvsdalgfeqavdvqeli
yhdenravvadwlnrhgwrataqsapdemrrvgrwgdgvpmaddkdafaefvtahrl

Sequence, based on observed residues (ATOM records):

>d2uyqa_ c.66.1.57 (A:) automated matches {Mycobacterium leprae [TaxId: 1769]}
vgttavmvaaaraaetdrpdalirdpyakllvtntgagalweamdaeaaamvehmrsyqa
vrtnffdtyfnnavidgirqfvilasgldsrayrldwptgttvyeidqpkvlayksttla
ehgvtptadrrevpidlrqdwppalrsagfdpsartawlaegllmylpataqdglfteig
glsavgsriavetsplhgdewreqmqlrfrrvsdaliyhdenravvadwlnrhgwrataq
sapdemrrvgrwgdgvpmaddkdafaefvtahrl

Timeline for d2uyqa_:

• d2uyqa_ first appeared in SCOP 1.75, called d2uyqa1
  
• d2uyqa_ appears in SCOPe 2.02
  
• d2uyqa_ appears in the current release, SCOPe 2.08