SCOPe 2.08: Domain d2bffb2: 2bff B:205-342

Lineage for d2bffb2 (2bff B:205-342)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (4 families)

5. Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (5 proteins)
   automatically mapped to Pfam PF02780

6. Protein Branched-chain alpha-keto acid dehydrogenase [52927] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52928] (23 PDB entries)
   Uniprot P21953 52-392

8. Domain d2bffb2: 2bff B:205-342 [128422]
   Other proteins in same PDB: d2bffa1, d2bffb1
   automated match to d1v16b2
   complexed with gol, k, mn, tzd

Details for d2bffb2

PDB Entry: 2bff, 1.46 Å

PDB Description: reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch

PDB Compounds: (B:) 2-oxoisovalerate dehydrogenase beta subunit

SCOPe Domain Sequences for d2bffb2:

Sequence; same for both SEQRES and ATOM records:

>d2bffb2 c.48.1.2 (B:205-342) Branched-chain alpha-keto acid dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
pyniplsqaeviqegsdvtlvawgtqvhvirevasmakeklgvscevidlrtiipwdvdt
icksviktgrllisheapltggfaseisstvqeecflnleapisrvcgydtpfphifepf
yipdkwkcydalrkminy

Timeline for d2bffb2:

• d2bffb2 first appeared in SCOP 1.73
  
• d2bffb2 appears in SCOPe 2.07